viii TABLE OF CONTENTS 



V. LOUSE FEEDING EXPERIMENTS UPON TYPHUS PATIENTS . . 41,^ 



1. Methods of Feeding 41 



2. Results of the Louse Feeding Experiments 43 



3. Table of Louse Feeding Experiments 44 



VI. EXPERIMENTS TO PROVE THE SPECIFICITY OF Rickettsia Prowa- 



zeki FOR TYPHUS 51 



1. Methods 51 



2. Protocols of Experiments 53 



3. Summary and Conclusions of the Experiments to prove the 

 Specificity of Rickettsia prowazeki for Typhus 109 



4. Table of Experiments in Proof of the Specificity of Ricket- 

 tsia prowazeki for Typhus 110 



VII. CULTIVATION EXPERIMENTS 113 



1. Technic 113 



2. Cases 113 



3. Results of Anaerobic Cultures 114 



4. Control Aerobic Cultures 114 



VIII. RICKETTSIA 116 



1. Historical Review 116 



2. Summary of Present Knowledge of Rickettsia 123 



3. Table of Rickettsias and Hosts 125 



4. Rickettsia and Trench Fever 130 



IX. Rickettsia Prowazeki IN LICE 132 



1. Smear Preparations of Lice 134 



2. In Sections of Lice 137 



3. The Recognition of Rickettsia 141 



X. TYPHUS IN GUINEA-PIGS 143 



1. Methods of Inoculation 144 



2. Clinical Course 145 



3. Gross Pathology 146 



4. Incubation and Duration of Fever 148 



XI. PATHOLOGY OF TYPHUS IN MAN 152 



1. Material 152 



2. Macroscopic Pathology 152 



(a) The skin 152 



(6) The blood 153 



(c) The heart . , 153 



