CH. XXXIII.] 



BILE. 



The following table gives some important 

 bile : 



503 

 of human 



Bile Mucin. There has been considerable diversity of opinion 

 as to whether bile mucin is really mucin. The most recent work 

 in Hammarsten's laboratory shows that differences occur in 

 different animals. Thus in the ox there is very little true mucin, 

 but a great amount of nucleo-proteid ; in human bile, on the 

 other hand, there is very little if any nucleo-proteid ; the mucinoid 

 material present there is really mucin. 



The Bile Salts. The bile contains the sodium salts of 

 ((implex amido-acids called the bile acids. The two acids most 

 i'iv|uently found are glycocholic and taurocholic acids. The 

 former is the more abundant in the bile of man and herbivora ; 

 the latter in carnivorous animals, like the dog. The most 

 important difference between the two acids is that taurocholic 

 acid contains sulphur, and glycocholic acid does not. 



Glycocholic acid (C^H^NOg) is by the action of dilute acids 

 and alkalis, and also in the intestine, hydrolysed and split into 

 glycocine or amido-acetic acid and cholalic acid. 



( ',,H4sN0 6 + 



[glycocholic acid] 



The glycocholate of soda has the formula 

 Taurocholic acid (261145X078) similarly splits into taurine 

 or amido-isethionic acid and cholalic acid. 



2 = C 2 H 5 N0 2 



[Rlyroriiie] [cholalic acid) 



|lniiriM-)i.ilii- :i.-i. 



2 = C 2 H 7 N0 8 S + C^H^A 



|!aiiriiir] [cholalic acid) 



