PHYSIOLOGY: HARRIS AND BENEDICT 373 



;abolism of an unknown subject. An analysis of the data of actual experi- 

 nentation on subjects at changing levels of nutrition shows that the changes 

 n metabolism are not proportional to those in body surface. Surface area 

 nay not be looked upon as a determining factor in basal metabolism. 



The closest prediction of the daily heat production of a subject can be 

 nade by the use of the multiple regression equations, 



For men, h = 66.4730 + 13.7516 w + 5.0033 s - 6.7550 a 



For women, h = 655.0955 + 9.5634 w + 1.8496 5 - 4.6756 a 

 vhere h = total heat production per 24 hours, w = weight in kilograms, 

 : = stature in centimeters, and a = age in years. These equations have 

 )een tabulated for values of weight from 25.0 to 124.9 kgm., for stature from 

 [51 to 200 cm., and for age from 21 to 70 years, so that the most probable 

 oasal metabolism of an unknown subject may be easily determined. 



Such tables should render service in clinical and other fields of applied 

 :alorimetry. Their usefulness has been demonstrated in testing the typical 

 )r atypical nature of series of metabolism measurements, in investigating 

 ;he differentiation of the sexes with respect to metabolic activity, of the 

 netabolism of athletes as compared with non-athletic individuals, and of 

 ndividuals suffering from disease. 



The detailed measurements and statistical constants, with full discussions 

 )f pertinent literature, are about to appear in Publication No. 279 of the 

 arnegie Institution of Washington. 



