Table II. Schedule of administration of preservative, Series VII. Cont'd. 



METHOD OF ADMINISTRATION. 



A slight variation in the administration of the preservative was 

 introduced by the fact that it was deemed important that the investi- 

 gation should include sulphurous acid in a gaseous state as well as in 

 combination as sulphites. The most convenient method for the 

 administration of the gaseous sulphurous acid was found to be by the 

 preparation of an aqueous solution of the acid of standard strength 

 taken, after dilution with water, as an ordinary drink. Water 

 proved to be a more convenient vehicle than milk or other beverages 

 for this purpose. 



In the form of sulphites the method of administration in capsules 

 was practiced. This method, as in the previous investigations, was 

 found not only to be the most convenient, but also, all things con- 

 sidered, the most desirable form in which to administer a substance 

 of this kind. 



Attention has been called in the previous reports to the distaste 

 which the subject would acquire for a food product in which he knew 

 the preservative had been mixed, and therefore less disturbance of 

 the mental equilibrium was caused by the administration of the cap- 

 sule, the envelope of which is itself a food product and would be soon 



[Cir. 37] 



