TABLE II. Schedule of administration of preservative, Series VIII. 



[In capsules.] 



Took preservative, but became sick immediately afterwards. 



SUMMARY OF RESULTS. 

 MEDICAL AND CLINICAL DATA. 



The observations made show that both benzoic acid and benzoate 

 of soda, when administered to healthy young men in the quantities 

 described, produce marked symptoms of discomfort and malaise in 

 the majority of cases. There was little difference noted in the effect 

 of the two forms of the preservative in the production of these 

 symptoms. The most common symptoms are nausea and headache, 

 which occurred in nine and eight cases, respectively. The nausea 

 resulted in vomiting in only three cases. Seven of the subjects com- 

 plained of weakness and also of burning and irritating sensations in 

 the esophagus. Hunger w r as increased in three cases, and indigestion 

 was especially noted five times. 



The fact that these symptoms were not produced in all cases illus- 

 trated a point prominently brought out in the previous investiga- 

 tes. 39] 



