work will be carefully considered and that there will be accorded 

 to it that measure of professional and public confidence which its 

 character merits. 



SUMMARY OF RESULTS. 

 CLINICAL AND MEDICAL DATA. 



A study of the clinica} and medical history of the men under 

 observation indicates that the administration of the salicylic acid 

 at first produces a stimulating effect upon the processes of solution 

 and absorption of the food materials from the alimentary canal. 

 There is a smaller proportion of the food products in the feces, both 

 in the individual cases and as a whole, during the preservative period, 

 and part of the after period is subject still to the effects of the admin- 

 istration of the preservative. There is also reported in the clinical 

 and medical history an increased appetite in the case of the majority 

 of the subjects. Altho the quantity of food which had been found 

 sufficient for the normal functions of the body during the fore 

 period is not diminished, and even to a slight extent in most instances 

 increases, a feeling of hunger develops in almost every case, show- 

 ing a disturbance of some kind in the metabolic process. The 

 nature of this disturbance is disclosed in the chemical studies, while 

 its observation is a prominent feature of the clinical and medical 

 history. Judged by the development of hunger alone the administra- 

 tion of the salicylic acid might be considered a stimulant. When, 

 however, all the functions of the body are in a normal state, there is no 

 need of a stimulant, and the effect produced by the administration 

 of the acid is evidently, therefore, an abnormal one. In cases where 

 it is advisable to stimulate temporarily the digestive organs an effect 

 such as that produced would be desirable if not continued too 

 long. The physiological history of the use of stimulants, however, 

 shows that they are temporary in their effects; that the increased 

 activity produced by them is at the expense of the total vitality of 

 the organ. Hence stimulants -are indicated only for temporary or 

 intermittent use. The truth of this statement is wholly established 

 by the subsequent data gathered from the clinical and medical history 

 of the subjects. The temporary hunger, while accompanied in a 

 number of cases by heaviness and uneasiness in the epigastric region, 

 does not cause any very great discomfort, and in the majority of 

 cases the abnormal desire for food soon decreases. The same quan- 

 tity or a slightly increased quantity of food is consumed thruout the 

 administration of the preservative. 



The loss of weight which is observed in almost all cases indicates 

 that the apparent stimulation of the digestive process is not 

 attended with any corresponding benefit in the building up of the 

 tissues of the body. Assuming, as is done constantly in these 



