6 



of nutrition by exciting the katabolic activities to a greater degree 

 than the anabolic. 



THE MICROSCOPIC BODIES IN THE BLOOP. 



There is an Increase in the number of red corpuscles in the blood 

 and also a slight increase in the number of white corpuscles during 

 the period of the administration of the preservative. The intensity 

 of the color of the^blood diminishes, however, both in the preservative 

 and in the after period. There is a marked decrease in the number 

 both of red and white corpuscles in the after period. The apparent 

 increase, therefore, in the preservative period is followed by a very 

 considerable decrease in the after period. No conclusion, favorable 

 or unfavorable, can be drawn from this observation regarding the 

 use of the preservative, tho apparently, if there is any effect 

 produced, it should be attributed to a favorable influence of the 

 preservative in increasing the number of red corpuscles. 



INFLUENCE OF THE PRESERVATIVE UPON THE URINE. 



VOLUME. 



But little influence of the salicylic acid on the volume of the urine 

 is noticed. The average quantity of urine excreted per day is very 

 slightly larger in the preservative period than in the fore period, for 

 the nine men taken together, while in the after period it is slightly 

 less. There is, therefore, a very slight tendency manifested, which 

 is of no particular significance, to increase the volume of the urine. 

 There is also noticed a slight increase in the total solids excreted in the 

 urine, and this increase is maintained in the after period. This obser- 

 vation is in harmony with that indicated by many of the other 

 phenomena which show that the salicylic acid has increased the 

 katabolic activities of the body. 



PRESENCE OF ALBUMIN. 



In so far as the limited observations made on this point in the 

 main experiment on the twelve men are concerned, the administra- 

 tion of the salicylic acid did not produce any notable effect upon the 

 occurrence of albumin in the urine. In the special study made sub- 

 sequently of four men, a marked tendency is shown to increase the 

 occurrence of albumin. 



MICROSCOPIC BODIES. 



The occurrence of microscopic bodies in the urine is a normal con- 

 dition, and therefore the only point which can be considered here is 

 to determine whether or not the exhibition of the salicylic acid tended 

 to increase or diminish their number. The mass data collected for the 

 nine men indicate that there was a tendency on the part of the sali- 

 cylic acid to increase the number of microscopic bodies in the urine, 



