CONTENTS 13 



PAGE 



CHAPTER XIV. ANTITOXINS AND RELATED ANTIBODIES .129 



Antibodies of Ehrlich's First Order, 129. Toxins, 129. Antitoxins, 131. Con- 

 stitution of the Toxin, 134. Constitution of Antitoxin, 134. Diagrammatic 

 Representation of Toxin and Antitoxins, 135. Preferential Union of Toxins with 

 Body-cells, 135. Antitoxins of Commercial Importance, 136. Manufacture of 

 Diphtheria Toxin and Antitoxin, 136. Preparation of Tetanus Toxin and Anti- 

 toxin, 143. Preparation of Other Toxins and Antitoxins, 145. Antienzymes, 145. 

 Other Antibodies Related to Antitoxins, 146. 



CHAPTER XV. AGGLUTINATION AND PRECIPITATION 147 



Antibodies of Ehrlich's Second Order, 147. Differentiation of Precipitation and 

 Agglutination, 147. Agglutination, 147. Precipitins, 154. 



CHAPTER XVI. CYTOLYSINS, INCLUDING BACTERIOLYSINS, AND HEMO- 



LYSINS 157 



Antibodies of Ehrlich's Third Order, 157. Cytolysins, 157. Group Cytolysins, 

 160. Bacteriolysins, 160. Hemolysins, 162. Fixation of Complement and Its 

 Utilization, 163. Cytotoxins, 165. 



CHAPTER XVII. OPSONINS AND PHAGOCYTOSIS 166 



Opsonins, 167. Opsonic Index, 169. Autogenic Vaccines, 173. Passive 

 Opsonic Immunization, 175. 



CHAPTER XVIII. ANAPHYLAXIS AND HYPERSUSCEPTIBILITY 176 



Phenomenon of Arthus, 176. Serum Sickness in Man, 176. Theobald Smith 

 Phenomenon, 177. Antibodies in Anaphylaxis, 177. Relationship of Ana- 

 phylaxis to Certain Body Reactions, 179. 



CHAPTER XIX. AGGRESSINS. . 181 



SECTION IV 



PATHOGENIC MICROORGANISMS EXCLUSIVE OF THE PROTOZOA 

 CHAPTER XX. MICROORGANISMS AS A CAUSE OF DISEASE 183 



Infectious Diseases, 183. Contagious Diseases, 183. Bacteria Normally Present 

 in the Body or on its Surface, 184. Types of Disease Produced by Microorgan- 

 isms, 186. How Bacteria Produce Disease, 187. Groups of Pathogenic Micro- 

 organisms Exclusive of Protozoa, 187. 



CHAPTER XXI. NON-SPECIFIC PYOGENIC Cocci 190 



Micrococcus Aureus, 192. Micrococcus Albus, 196. Micrococcus Citreus, 

 196. Micrococci of Uncertain Significance, 196. Streptococcus Pyogenes, 197. 

 Streptococcus Lacticus, 204. 



CHAPTER XXII. SPECIFIC INFECTIOUS DISEASES PRODUCED BY Cocci. . 207 



Streptococcus Equi, 207. Streptococcus Gallinarum, 210. Streptococcus Sp., 

 211. Streptococcus Sp., 213. Other Streptococci of Uncertain Significance, 

 214. Streptococcus Pneumonias, 215. Micrococcus Meningitidis, 218. Micro- 

 coccus Intracellularis Equi, 220. Micrococcus Melitensis, 221. Micrococcus 

 Caprinus, 222. Micrococcus Gonorrhoeae, 224. Micrococcus Ascoformans, 226. 



CHAPTER XXIII. NON-SPECIFIC PYOGENIC BACILLI 228 



Bacillus Pyocyaneus, 228. Bacillus Pyogenes Suis, 230. 



CHAPTER XXIV. DIPHTHERIA GROUP 231 



Bacillus Diphtheria, 231. Bacillus Pseudodiphthericus, 236. 



