120 VETERINARY BACTERIOLOGY 



(6) Those of a defensive or reparative nature, as production 

 of new tissue and invasion of lesion by phagocytic 

 leukocytes. 



(1) Increased functional activity. 



(2) Increased formative activity, cell growth, and division. 

 2. Produced at a distance from the bacteria, due directly or 



indirectly to poisonous substances produced by the 

 bacteria, 

 (a) In special tissues. 



(1) Changes resulting from damage. 



(2) Changes of a reactive nature in blood-forming organs. 

 (6) General anatomical changes, effects of malnutrition or 



of increased waste. 

 B. Changes in metabolism, fever, etc. 



