SPECIFIC INFECTIOUS DISEASES PRODUCED BY COCCI 211 



sufficient acid to coagulate milk, but differs culturally otherwise 

 in no marked degree from Sir. pyogenes. 



Pathogenesis. Experimental #wctence. Inoculations of pure 

 cultures into fowls, rabbits, mice, and swine are fatal, while those 

 into the guinea-pig, sheep, and dog are not. 



Disease and Lesions Produced. The disease is a typical sep- 

 ticemia, marked by parenchymatous degenerations and hemor- 

 rhage. Norgaard and Mohler state that fowls frequently die in 

 twelve to twenty-four hours after the first symptoms. 



Immunity. Little is known relative to the causal organism 

 and its products. Probably they differ little, if at all, from those 

 of Str. pyogenes. The dis- 

 coverers state that active 

 immunity may be conferred 

 by the injection of bouillon 

 culture filtrates and by vac- 

 cination with killed cult- 

 ures, and passive immunity 

 by the injection of the 

 blood-serum of an immun- 

 ized animal. 



Bacteriologic Diagnosis. 

 The organism may be 

 identified as a gram-positive 

 organism in smears from the Fig sg ._ Streptococcus ga mnaru m (Mag- 

 blood and internal organs nusson). 



and by culture. 



Transmission. According to the German authorities, the 

 disease is not very contagious, but its appearance in considerable 

 numbers of fowls at one time remains unexplained. 



Streptococcus Sp. 



Synonym. Streptococcus of Ostertag. 



Disease Produced. Contagious granular or verrucose vaginitis 

 in cattle. 



Ostertag, in 1898, isolated and cultivated a Streptococcus 

 from the purulent discharge and from the deeper layers of the 

 mucous membrane in cases of infectious vaginal catarrh. His 



