MOLD OR HYPHOMYCETE GROUP 411 



jointed from the tip of the conidiophore. Chlamydospores may 

 form in the hyphae. 



Isolation and Culture. The organism may be isolated without 

 difficulty from the lesions of the disease. A distinctly acid medium 

 should be used. On most nutrient media it develops superficial, 

 spherical, white, waxy to granular colonies. Gelatin is not 

 liquefied, nor is blood-serum. 



Pathogenesis. The organism, when injected intravenously 

 into rabbits, produces a fatal infection, not unlike a generalized 

 infection with a Blastomyces. Typical thrush has been pro- 

 duced in the mouth of young animals and birds by inoculation. 

 The disease generally occurs in the mouth of sucklings, usually as 

 a benign infection. It is characterized by the formation of white 

 patches on the mucous membrane, varying in size from points to 

 considerable areas. The infection may extend to the pharyngeal 

 or laryngeal mucosse; rarely metastatic infection of internal 

 organs may occur. 



