COMPLICATIONS 23 



nous doses produce death from septicemia quite 

 regularly. The pigs that die in less than seventy- 

 two hours may show as lesions congestion of the 

 lymph glands and various parenchymatous or- 

 gans, or, more rarely, petechial hemorrhages in 

 the kidneys and heart, indistinguishable from 

 those observed in acute hog cholera. In the cases 

 in which the disease runs a less rapid course, there 

 is a rather constant tendency for joint lesions of 

 an inflammatory nature to form, and, contrary to 

 what might be expected, pleuritis and pneumonia 

 appear much less frequently than these joint le- 

 sions. Rarely do checks kept with these experi- 

 mental animals contract disease. 1 



The symptoms that appear in pigs artificially 

 infected with large intravenous doses of Bact. 

 suisepticum are observed in a very few hours 

 after the injection. There is rapid breathing, 

 sometimes an extreme degree of dyspnea, or the 

 respiratory disturbance may manifest itself in 

 1 ' thumping. ' ' The appetite is suspended, the tem- 

 perature is moderately high (104-105.5 F.) and 

 there is an anxious facial expression. A general 

 stiffness is practically always observed, and 



*In our own experiments, in which more than 100 pigs were 

 exposed in pens with pigs artificially infected with intravenous 

 injections of Bact. suisepticum, 3 contracted disease and 2 died. 

 Bact. suisepticum was recovered from the blood and various 

 parenchymatous organs of the dead animals. We know of no 

 other well authenticated instances in which like transmission has 

 occurred. 



