GRAFTING GERMS OF DOGS' TEETH. XXV11 



made a wound in a cock's comb, pressed the root into 

 it, and fastened it with threads. The cock was killed 

 some months after, and I injected the head with a very 

 minute injection. I then put the comb into a weak 

 acid. The tooth was softened, and I divided it longi- 

 tudinally. Its vessels were well injected, the external 

 surface adhering to the comb by vessels similar to the 

 union of a tooth with the gum and sockets." * 



* MM. E. Magitot, C. Legros, and C. Robin have experimented 

 in transplanting the follicles or germs of dogs' teeth, an account 

 of which appears in "Comptes Rendus" for 1874. They say : 



" Our experiments comprised 88 grafts, mostly from newly-born 

 dogs, but some were 22 and even 58 days old. The animals 

 were invariably sacrificed by the pricking of the bulbs, and 

 the jaws were opened at once, to lay the follicles bare. One-half 

 of both jaws thus served to supply the grafts, while the other 

 was kept for a standard of comparison. The dogs on which the 

 grafts were applied were usually adults, but sometimes of the 

 same age and bearing as those that supplied them. The germs 

 were rapidly isolated from the dental gutters, and introduced at 

 once. In some instances they were dipped for a few minutes in 

 the blood's serum of the sacrificed animal, which was kept by 

 the bath (bain-marie) at a temperature of from 30 to 35 C. 

 They were introduced under the skin of the nape of the neck, 

 the top of the head, and the dorsal and lumbar regions. In 36 

 cases the process of application consisted of a simple incision and 

 the introduction of the graft 2 or 3 centimeters from the open- 

 ing, which was closed by two sutural stitches. In the other 52 

 cases a special trocar of an interior diameter of 7 millimeters was 

 used, which allowed a swifter and surer transplantation, but it 

 did not appear to exert an appreciable influence on the results. 



" Ten grafts were made from newly-born dogs on adult guinea- 

 pigs, divided as follows : Whole follicles, 6 ; isolated enamel- 

 organs, 3 ; bulb alone, 1. The results were all negative caused 

 by resorption and suppuration corroborating M. Bert's experi- 

 ences in grafts between animals of different zoological orders. 



" The 78 other grafts were made on newly- born, young, and 

 adult dogs, and were maintained from 13 to 54 days. The 25 

 grafts that remained 54 days resorbed themselves. The experi- 

 ments in detail were as follows : 1. Isolated whole follicles, 26. 

 2. Follicles with a portion of the maxillary bone, 5. 3. Isolated 



