54 THE LIVER. 



of note that the excretion of sugar in the urine gene- 

 rally follows. 



Does the cause of the accumulation of bile in the 

 blood depend upon metamorphosis of a morbid character 

 in the blood itself? or on a deranged innervation acting 

 upon the circulation and respiration as already referred 

 to ? or does it arise from congestion of the liver, fol- 

 lowed by the mal-assimilation of sugar ? If so, then I 

 maintain that a preparation of the CURARI may prove a 

 potent remedy in Jaundice of this type, as Claude 

 Bernard has very clearly pointed out, that one of the 

 pathogenetic effects of this poison on the system is to 

 give rise to CONGESTION OF THE LIVER, and to the 

 excretion of sugar in the urine. I venture to direct the 

 attention of my colleagues to this fact, and shall be 

 glad to receive any hints on the subject, as I am about 

 to institute a series of experiments with " CURARI" in 

 hepatic derangements, particularly congestion, a form 

 by no means uncommon in fenny districts. 



6. Jaundice may take place from pyaemic infection 

 of the blood. Marechal, in 1828, was about the first to 

 observe that individuals, in whose bowels pus existed, 

 the skin, conjunctive, and other tissues of the body, 

 exhibited a more or less jaundiced appearance. This 

 has since been noticed by many other observers. Arsc- 

 nicum, and perhaps Lachcsis, or Curari, would prove 

 potent remedies, combined with a series of pack, or 

 Turkish baths. 



7. Jaundice is no uncommon symptom of divers 

 forms of eruptive and other fevers. We find it in close 

 alliance with typhus, particularly the petechial or epi- 

 demic form. We encounter it running side by side with 



