156 SIMPLE HYPERTROPHY 



substance was congested, dense and firm, and of a 

 uniform brownish red colour. In 1854, Frerichs exa- 

 mined another liver, that of a woman's, aged 37, who 

 had suffered from " diabetes mellitus," but who died 

 from caries of the petrous portion of the temporal bone, 

 and erysipelas of the face, which presented the same ab- 

 normal characters. Stockvis, in 1856 ; Claude Bernard, 

 in 1855 ; Hiller, in 1843 ; Griesinger, in 1859, met with 

 similar cases. In 1870 a similar case came under my 

 own observation ; it was that of a near relative who came 

 to consult me from North Wales for diabetes mellitus. 

 The specific gravity of his urine was as high as 1050, 

 and held in solution a large quantity of sugar ; there was 

 considerable enlargement of the liver,which was uniform 

 all over; a carefully selected diet, a Turkish bath 

 daily, 1 '<><// ///?//////>/, and Nux Vom, internally; and u 

 compress sufficiently capacious to cover both hypo- 

 chondriac regions, (which brought out in ten days a 

 tremendous crop of pustules), sufficed to dispel every 

 vestige of sugar, and reduce the enlarged liver to its 

 normal stain lard within the brief period of six weeks. 



' Hypertrophy" of the liver, in company with 

 "hypertrophy" of the spleen and lymphatic glands, 

 frequently attends that condition of the system, known 

 " LEUKCEMIA." Virchow, Bennett, Vogel, Freidreichs, 

 and others, have recorded a series of observations in 

 proof of the occurrence of an altered nutrition of the 

 liver, in conjunction with THIS abnormal condition of 

 the blood. 



It has been noticed by physicians who have practised 

 in the tropics, that after some years' residence in those 

 countries the liver is wont to increase in size without 



