KEPORT OF THE BUEEATJ OF ANIMAL H5TDUSTBY. 67 



Inflammatory adhesion of liver to diaphragm. Mesenteric glands 

 nearly as large as hen's eggs, mottled, pale red. About twelve ulcers 

 one-quarter to one-half inch across in lower ileum; base depressed 

 and covered with a thin yellow layer; outline irregular; not con- 

 nected with Peyer's patches. Valve thickened and ulcerated. Sev- 

 eral ulcers in caecum; a large projecting slough attached to one of 

 them. A gelatine and a liquid culture from the spleen contain hog 

 cholera bacteria only. A liquid culture from the pleura 'remains 

 sterile. 



A rabbit inoculated from the hepatized lung tissue died on the 

 eighth day. Slight fibrinous exudate on intestines, diffuse coagula- 

 tion necrosis in liver, spleen much congested. Immense number of 

 hog cholera bacteria in spleen and liver. Cultures pure. A plate 

 made from the same bit of (pig's) lung tissue contains about fifty 

 colonies resembling hog cholera. 



No. 6, large black male, died last night. Extensive serp-nbrinous 

 infiltration of subcutis from axilla to pubis and over right thigh. 

 The subcutis has a gelatinous aspect. Spleen much congested. 

 Lungs normal. In cover-glass preparations from spleen large bacilli, 

 with ends square. Cultures in gelatine and beer infusion remain 

 sterile. Animal probably died of malignant osdema. 



November 21. No. 7, medium-sized male, died yesterday. Tem- 

 perature of air varying from 26 to 50 F. Omentum deeply red- 

 dened. Spleen enlarged, soft; small hemorrhages under capsule 

 one-eighth inch across. Liver imparts a sensation of grittiness when 

 cut. Cortex of kidneys dotted with hemorrhagic points. The patch 

 of mucous crypts about valve in caecum dark, pigmented; no ulcer- 

 ation. Mucosa of stomach hemorrhagic in fundus. Thorax half 

 full of blood-stained serum and some fibrin stretching from lung 

 surface to walls ; small quantity of fibrin in pericardial cavity. Lung 

 tissue infiltrated with blood (pulmonary hemorrhage). Two ventral 

 lobes collapsed; subpleural hemorrhagic patches. A cover-glass 

 preparation from spleen contains numerous hog cholera bacteria. 

 In each needle track of a gelatine culture, countless colonies. A 

 liquid culture from a bit of spleen tissue contains hog cholera bacteria 

 only. 



No. 8, small female, died yesterday. Patches of skin on ventral 

 aspect of limbs and groin reddened. Minute petecchiae under serosa 

 of ventral abdominal walls. Spleen very large, congested. Some 

 delicate fibrils stretched over coils of intestine. Liver cirrhosed. 

 Glands of mesentery and meso-colon enlarged; cortex hemorrhagic. 

 Fundus of stomach moderately congested. In caecum are black pig- 

 ment spots resembling former hemorrhage, chiefly on the summit 

 of folds. In upper colon ulcers about three to a square inch, each 

 one-fourth inch in diameter, and covered by a convex, projecting 

 yellowish slough. Ulcers found down to rectum. Small quantity 

 of clear serum and a few fibrils in pleural cavities and pericardium. 

 Left ventral and tip of right cephalic lobe collapsed. A gelatine and 

 a liquid culture made from a bit of spleen tissue contain hog cholera 

 bacteria and a butyric bacillus which slowly liquefies the gelatine. 



No. 9, small male. Diffuse reddening of ventral aspect of body es- 

 pecially marked on limbs. Spleen, lymphatics, and kidneys normal. 

 A small abscess in pelvis attached to bladder, probably caused by 

 castration. Venous congestion of vessels of meso-colon. The trans- 

 verse folds of niucosa of colon covered by very thin yellowishpatches 

 of necrosis. Feces hard, distending the large intestine. Cephalic 



