68 EEPOET OF THE BTJEEAU OF ANIMAL UTDUSTEY. 



and ventral lobes of left lung solid, plainly mottled. The bronchioles 

 and alveoli filled with consistent plugs of cellular exudate, Remain- 

 der of lungs normal. Owing to small size of spleen, two liquid cult- 

 ures were made, each with a bit of spleen tissue. In both, hog 

 cholera bacteria alone appeared. A rabbit inoculated with hepatized 

 lung tissue remains well for weeks after. A plate culture therefrom 

 is liquefied in two days. 



No. 10, small castrated male, died yesterday. Has been sick for 

 some time according to overseer of farm. Spleen not enlarged. In- 

 flammatory changes in pelvis due to castration. Stomach slightly red- 

 dened and bile-stained. One large ulcer on ileo-caacal valve one-half 

 inch across, black, with yellowish margin. A few very superficial 

 ulcers in caecum. Lungs normal, left somewhat hypostatic. Two 

 cultures made with bits of spleen contain both hog cholera bacteria 

 and butyric bacilli. 



No. 11, dying, killed by being bled from brachial vessels. Lungs 

 normal. Spleen small. Liver slightly cirrhosed. Two ulcers in 

 caecum; slight superficial necrosis in colon. A liquid culture made 

 from a bit of spleen contains hog cholera bacteria on following day. 



November 23. No. 12, small white male, died yesterday. Median 

 line of ventral aspect of body much reddened, limbs slightly so; ex- 

 travasation under skin and into muscular tissue over sternum. Much 

 blood-stained serum in peritoneal cavity; spleen very largo, dark. 

 In kidneys, cortex and base of pyramids deeply reddened. In caecum, 

 slight traces of superficial necrosis. Anterior and cephalic lobes of 

 both 1 ungs collapsed. Blood-stained serum in pericardium. Numer- 

 ous hog cholera bacteria on cover-glass preparations of spleen pulp. 

 In a gelatine culture from the spleen countless colonies appear in each 

 needle track. A liquid culture made with platinum wire contains 

 hog cholera bacteria on following day. A rabbit inoculated from 

 the collapsed lung tissue died on the tenth day. Spleen engorged; 

 numerous foci of coagulation-necrosis in liver, involving each one or 

 more acini; extensive necrosis along border of left lobe. Ecchymo- 

 sis of pyloric valve and duodenum; hemorrhagic foci in lungs, about 

 fifteen in each lung, one-eighth inch to three-sixteenths inch in di- 

 ameter. Examination of the spleen shows numerous hog cholera 

 bacteria. A gelatine culture contains countless colonies in each 

 needle track. 



No. 13, small female, died yesterday. Skin on ventral aspect of 

 limbs and over pubis reddened. Spleen greatly enlarged, congested. 

 Lungs normal. A few lobules in ventral and right cephalic lobe col- 

 lapsed. Liver slightly cirrhosed. Stomach distended with food. 

 Large patch of mucosa in fundus reddened. Caecum and colon 

 contain numerous ragged depressed ulcer ations. Valve entirely 

 encircled by ulceration. Contents of intestine liquid, yellow. A 

 gelatine and a liquid culture inoculated with a platinum wire thrust 

 into spleen remain sterile. No bacteria seen in cover-glass prepara- 

 tions. 



No. 14, small female, weight about 50 pounds. Considerable red- 

 dening of the skin over ventral aspect of body and limbs; especially 

 marked along median line. Superficial inguinals enlarged, of a mot- 

 tled pale and deep red on section. Spleen very large, 12 inches long, 

 2 inches broad, and five-eighths to three-fourths inch thick at hilus; 

 gorged with blood, friable. A small number of punctiform hemor- 

 rhages in cortical portion of kidneys. Glands or mesentery and of 

 colon enlarged and congested. Deep reddening of several square 



