REPORT OF THE BUREAU OF ANIMAL INDUSTRY. Tf 



gested.' Spleen barely congested. Mucosa of lower ileum completely 

 ulcerated. Similarly that of caecum and upper colon, but more se- 

 verely so as to make the intestinal wall very triable. In lower colon 

 the ulcers are isolated. Lungs and heart normal. In a roll culture 

 from a bit of spleen tissue about one hundred colonies of hog cholera 

 bacteria appeared. 



No. 48, medium-sized black and white female, died last night. Su- 

 perficial inguinals enlarged, pale. Abdominal lymphatics in general 

 with cortex hemorrhagic. Spleen congested ; surface covered with 

 numerous elevated blood-red points. Liver extensively cirrhosed. 

 Mucosa of ileum dotted with petecchiae. It contains about fifteen 

 ulcers, not limited to Peyer's patches, with longer diameter trans- 

 verse, in some cases encircling the tube. The ulcer is covered by a 

 thin, yellow slough. One ulcer, one-half inch across, in caecum, and 

 two in colon. About one-half pint of straw-colored serum and a mass 

 of semi-gelatinous pale coagulum the size of a fist in each pleural sac. 

 Lungs but partly collapsed, pleura slightly roughened. Interlobular 

 tissue of dependent lobes distended with serum, parenchyma oedem- 

 atous, so as to sink in water. Bronchi contain a slight amount of 

 reddish fluid. In a roll culture from a bit of spleen pulp about two 

 hundred colonies of hog cholera bacteria appear. 



December 24=. No. 49, large, black and white. Spleen gorged with 

 blood. Lymphatics generally pale ; liver cirrhosed. Caecum and 

 colon with walls thickened and very friable ; mucosa entirely ulcer- 

 ated. One ulcer in rectum. A roll culture from the spleen melted, 

 but found to contain on examination only hog cholera bacteria, 



DISEASE IN HEALTHY PIGS CAUSED BY MATERIAL FROM THIS EPI- 

 ZOOTIC. 



November 21. Two pigs (Nos. 434, 435), about two months old, fed 

 with spleens from several of the preceding cases. Two days later a 

 few more spleens were given them. Both became sick a few days 

 later and died November 28, about twelve hours apart. 



No. 434. Spleen slightly enlarged, full of blood. All glomeruliof 

 kidneys show as hemorrhagic points ; lymphatics moderately con- 

 gested. Stomach along entire f undus deeply congested. Superficial 

 small ulcers in caecum and colon; in the caecum they are covered by 

 a projecting slough. Bight ventral and cephalic lobes collapsed, the 

 former developed into broncho-pneumonia (catarrhal injection of 

 small air tubes and alveoli). A few lobules of left principal lobe in 

 the same condition. Hog. cholera bacteria in the spleen as deter- 

 mined by a gelatine and a liquid culture. A rabbit was inoculated 

 with a bit of lung tissue and a plate culture made. This developed 

 countless colonies, non-liquefying, alike, shown to be motile hog 

 cholera bacteria. Rabbit dies on sixth day. Spleen moderately con- 

 gested; contains many hog cholera bacteria. In liver, minute foci 

 of necrosis. A gelatine culture from the spleen contains numerous 

 colonies of hog cholera bacteria. 



No. 435. Spleen enlarged, covered with hemorrhagic elevations. 

 Kidneys hemorrhagic as in No. 434. Stomach near pylorus deeply 

 congested. Caecum and entire colon covered with a dirty yellowish 

 and blackish slough. Eight and left ventral lobes, a small portion 

 of right principal and left cephalic affected with broncho-pneumonia. 

 Cultures from the spleen of this animal were confused with those of 



