78 EEPOET OF THE BTTBEAU OF ANIMAL INDUSTRY. 



another pig (No. 25), but one set remained sterile; the other con- 

 tained hog cholera bacteria, and it is highly probable that the fertile 

 cultures belonged to this animal. 



A few additional cases are cited to show the infectious nature of 

 this outbreak. 



Nos. 436 and 437 were placed, November 27, in the infected pen 

 containing the two preceding animals. They were also fed por- 

 tions of hog cholera viscera later on. 'No. 436 was found dead De- 

 cember 27. Red blotches on skin of ventral aspect of body. Super- 

 ficial inguinals hernorrhagic. Other lymphatics enlarged* but pale. 

 Spleen, slightly congested. Mucosa of caecum and colon deeply 

 congested and dotted with considerable number of small ulcers. A 

 roll culture from the spleen melted, but contains only hog cholera 

 bacteria according to microscopic examination. No. 437 did not take 

 the disease. 



Nos. 449 and 452, placed in the same pen December 17, but not fed 

 with infectious matter, died December 29. The lesions were some- 

 what different from those usually found, and are briefly as follows: 



No. 452. Spleen and lymphatics not enlarged. Large quantity of 

 serum and fibrinous coagula in abdomen. Viscera generally agglu- 

 tinated. Lungs glued to chest wall by a recent exudate. Pericar- 

 dium distended with serum and coagula. Lung tissue not affected. 

 Kidneys deeply reddened. Mucosa of csecum and colon entirely 

 covered with a thin layer of diphtheritic exudate; when scraped 

 away a deeply reddened surface is exposed. Numerous small, deep 

 ulcers present. A roll culture of spleen, also melted from the heat 

 of laboratory, contains only hog cholera bacteria. In No. 449 the 

 lesions were the same, excepting the pericarditis. The ulceration of 

 large intestine less extensive. 



Two very instructive cases of hog cholera were caused by simply 

 exposing pigs on an infected asphalt floor in a pen adjoining cases of 

 the disease. 



Nos. 464 and 466, about three and one-half months old, exposed with 

 six others January 4. 



No. 464 died January 11. Superficial inguinals normal. Those 

 in abdomen much tumefied and hemorrhagic throughout. Spleen 

 enlarged, friable, with hemorrhagic points. Several patches of mu^ 

 cosa in fuiidus of stomach one-fourth to one-half inch across, cov- 

 ered with blood clots. In large intestine only a few scattered petec- 

 chiee on mucous membrane. Some subpleural hemorrhages in lungs; 

 lung tissue normal. Scattered petecchise on epicardium of auricles 

 and ventricles. On cover- glass preparations from spleen pulp a mod- 

 erate number of bacteria were present. In several roll cultures only 

 colonies of hog cholera bacteria appeared. 



No. 466 died January 13. Skin of ears, throat, nose, limbs, and 

 belly deeply reddened. Spleen as in No. 464. A few petecchise on 

 epicardium. Kidneys as in No. 464. Urine contains blood. The 

 mucosa of large intestine in general deeply congested and studded 

 with about fifty ulcers one-fourth inch across. Meso-colic and re- 

 tro-peritoneal lymphatics with cortex hemorrhagic. Stomach as in 

 No. 464. Lungs normal, excepting collapse of two-thirds of ventral 

 lobes. Roll cultures from a bit of spleen pulp gave the same result 

 as in preceding case. 



