92 , REPORT OF THE BUREAU OF ANIMAL INDUSTRY. 



was filled with food, some small erosions of the mucous membrane. In the large 

 intestine, the mucosa of caecum dark-red, almost blackish, and covered with 

 large ragged ulcerations only 1 millimeter or 2 millimeters deep. The membrane 

 appeared as if gnawed. The ileo-caecal valve is almost completely surrounded 

 by ulceration, the base of the ulcers being blackish, and the mucosa much puck- 

 ered. The colon is bright red, dotted with darker points, and covered with small 

 ulcerations, circular as if punched out. The base of the ulcers is concealed by a 

 creamy mass, the border slightly thickened and intensely reddened. In some places 

 the ulcers number five or six to a square inch. Besides these small ulcers there are 

 several about one-half inch across, resembling the ragged ulceration in the caecum. 

 The contents of intestine resemble lumps of sand and mud, some extremely hard. 

 Sections through a few of the small circular ulcers show that they have arisen 

 around the mouths of mucous glands. 



On opening thorax, lungs collapse. Slight fibrous adhesion of right lung to tho- 

 racic wall near diaphragm. In each lung the cephalic, ventral, and a small portion 

 of the principal lobe, as well as the small azygos lobe, solidified. The hepatized 

 portions are bright red, dotted with very minute, closely-set, grayish spots, well shown 

 in fig. 2, Plate III. Examined with a lens these spots have a nebulous appearance. 

 On section this same mottled appearance. A few lobules an d groups of lobules are 

 converted into greenish-yellow, consistent, cheesy masses. Trachea and larger 

 bronchi filled with whitish foam. The smaller bronchi clogged with viscid mucus 

 inclosing air bubbles. Cover-glass preparations of alveolar exudate contained cocci, 

 of the spleen no bacteria of any kind. Cultures from the surface of the pleura re- 

 mained sterile; a liquid culture from the spleen contained three or four forms of 

 bacteria. One of these was evidently the microbe found in former cases. A second 

 form, a motile bacillus, isolated from this culture with the aid of gelatine plates, re- 

 sembled the bacterium of hog cholera in some features, differing from it in others. 

 Without giving these, suffice it to say that a rabbit inoculated subcutaneously 

 with one-third cubic centimeter liquid culture was killed in ten Hays. The lesion 

 was purely local: extensive suppuration of the connective tissue of the inoculated 

 thigh. The lymphatic glands .of axilla on the same side enlarged, one of them 

 hemorrhagie throughout. The internal organs were normal; no evidence of those 

 lesions always following inoculation with hog cholera bacteria. 



March 8 a rabbit was inoculated by pricking both ears with a lancet and insert- 

 ing into the wound some of the alveolar exudate from the solidified lung tissue. No 

 result. Another rabbit was inoculated with the same lung tissue a week later, 

 which had been meanwhile kept in the refrigerator. A small bit of lung tis- 

 sue was placed beneath the skin of the thigh and the wound closed with a stitch. 

 It was killed a week later, though apparently well. A large mass of cheesy pus 

 was found at the place of inoculation in the subcutis. Internal organs normal. 

 Two mice were inoculated March 8 by placing bits of lung tissue beneath the skin 

 at the root of the tail. They died March 13 and 14, respectively. In the heart's 

 blood of both the characteristic bacteria found hitherto, and showing the polar 

 stain very clearly, were found in large numbers. Cultures therefrom corroborated 

 the microscopic examination. A table giving the inoculations is appended: 



Pig No. 408, died March 5. 



Another pig (No. 409) had been with Nos. 405 and 406 before January 31. Since 

 February 1 this animal began to fail. It became emaciated and weak, diarrhea 

 set in, a cougli was heard when the animal was incited to move. It died March 20. 

 Body very thin; skin of ventral aspect covered with elevated brownish scales one- 

 eighth to one-fourth inch in diameter, easily torn away, and involving only the epi- 

 dermis. Petecchire had been observed in the same situation during lif e ; superficial 



