EEPOKT OF THE BTJKEAU OF ANIMAL INDUSTKY. 129 



hepatized tissue varying in size, the largest probably 1| inches in diameter. The 

 hepatization is chiefly of the grayish variety, the tissue being very hard to the touch. 

 Some of these masses contain necrotic foci. The cephalic lobes are replaced by 

 masses of collapsed tissue interspersed with emphysematous tissue. Bronchial 

 glands very large, pale whitish on section. In each bronchus a thin, cylindrical, 

 dark clot embedded in much glairy mucus. Lung worms in the blind end of both. 

 Cover-glass preparations stained in gentian violet show leucocytes chiefly, with many 

 polar-stained cocci located around the nuclei and very likely embedded in the cell 

 protoplasm. 



A rabbit inoculated from this lung tissue, very sick thirteen days later, was chlo- 

 roformed. The place of inoculation is occupied by an abscess situated on thigh and 

 abdomen, and firmly attached fascia. No peritonitis. Spleen very large, of a gran- 

 ular appearance, the size due not to engorgement but hyperplasia. The larger cells 

 have their protoplasm filled with deeply stained granules. A few hog cholera ba- 

 cilli can be seen. In the liver a few acini have undergone coagulation-necrosis. 

 Cultures in cigar from the abscess and spleen contain only hog cholera bacilli. It is 

 very probable that the swine plague bacteria were destroyed in the organism of the 

 rabbit as indicated by the large abscess and the condition of the spleen. 



No. 15, control animal, died October 4. Spleen very large and gorged with blood. 

 The various lymphatic glands of abdomen, excepting those of mesentery, hemor- 

 rhagic throughout. Liver and kidneys not affected. Stomach filled with food. 

 In the lowest 3 feet of ileum are a large number of ulcers varying from the size 

 of a pin's head to one-half inch across. The smallest ones are simply superficial 

 sloughs. As they grow larger they become more and more excavated with thick- 

 ened, puckered periphery. There are also four or five large ulcers of the same ap- 

 pearance encircling the tube transversely. They are all stained deep yellow. The 

 serosa beneath these opaque. The mucosa of the caecum and about 6 inches of the 

 colon is converted into a tough, partly yellowish, partly blackish necrotic mass, 

 closely adherent to the muscular coat. Wall in general much thickened. Lower 

 down in the colon there are about six oval ulcers three-quarters inch across, with 

 center black, periphery yellowish (resembling buttons), the whole slightly elevated. 

 The neoplastic growth beneath the superficial slough whitish, firm, extending into 

 muscular coat. Farther down a similar ulcer 2 inches across. 



Lungs adherent to costal pleura by their anterior portion and to pericardium. 

 The left ventral and a portion of cephalic lobe solid. Tissue grayish-red on section. 

 A slight pressure forces from the air tubes a thick milky fluid. The principal lobe 

 much congested and cedematous. Of the right lung the ventral is solid and like 

 the corresponding left lobe, excepting that the contents of the air tubes is consistent, 

 like putty, and can be squeezed out in the form of cylindrical plugs. A portion of 

 the azygos lobe also hepatized. The curdy plugs made up almost entirely of agglu- 

 tinated pus corpuscles. The thoracic lymphatics with hemorrhagic cortex. Eight 

 heart contains dark, semi-coagulated blood, no white thrombi. 



This case did not present what might be considered swine plague lesions, judg- 

 ing from the foregoing cases and from previous experience. The lung tissue rubbed 

 on covers contained very few bacteria of any kind. A roll culture on the fifth day 

 contained many colonies of hog cholera bacteria. A rabbit inoculated from lung 

 tissue died in twelve days with very large spleen, coagulation-necrosis in liver, and 

 hemorrhagic duodenum. Only hog cholera bacteria obtained from its organs. 

 From the spleen of the same pig a liquid and an agar culture contained only hog 

 cholera bacilli. 



It is of course impossible to say "whether the lung lesions were due to the swine 

 plague germ or not. Certain it is that these organisms die out quite rapidly in 

 lesions as they advance in age, and may thus escape detection. In this case death 

 was due primarily to hog cholera, as the hemorrhagic condition of the lymphatics 

 and the culture indicate. 



October 8, No. 6, control animal, found dead this morning. Spleen enormously 

 enlarged. Lungs contain numerous hemorrhagic foci. A small region of one an- 

 terior lobe collapsed. No hepatization. From fifteen to twenty ulcers in large in- 

 testine. Two cultures from spleen remain sterile. 



Nos. 13, 16, and 17 are interesting cases, in that they all presented the lesions of 

 both hog cholera and swine plague in an aggravated form. Nos. 16 and 17 were 

 previously fed with the spleen and large intestine of the Baltimore pig (No. 19) be- 

 fore they were placed in the infected pen September 24. No. 17 was found dead 

 October 9 ; Nos. 13 and 16, October 11. 



No. 13, control animal. Skin over pubic region, along median line of abdomen, 

 inside of limbs, and on throat considerably reddened. Superficial inguinal glands 

 hemorrhagic. Spleen slightly enlarged, dark. Abdominal cavity contained about a 

 pint of fluid, dark-cotored fecal matter which had escaped from a perforation in 



12057 A I --9 



