130 EEPOET OF THE BUEEAU OF ANIMAL INDTTSTEY. 



walls of colon. Extensive pale-yellowish exudation matting the various organs 

 together. Caecum and colon extensively ulcerated. Lungs diseased. Exudative 

 pleuritis gluing lungs to chest wall. Left lung entirely hepatized with exception 

 of a small region near caudal border. Principal lobe in stage of red hepatization. 

 Ventral lobe in general red on section, with numerous small wavy lines and circles 

 or ovals of a grayish color, representing perhaps cell infiltrations about air tubes. 

 The latter plugged with caseous masses. On this lobe the pleuritic exudate was 

 from one-sixteenth to one-eighth inch thick. Of the right lung the whole ventral 

 lobe was solid, red, mottled faintly with gray ; cut surface smooth. Portion of the 

 cephalic lobe in the same condition. Azygos lobe normal. Bronchial glands en- 

 larged, pale pink on section. 



In the red hepatized lung tissue and pleuritic exudate a large number of swine 

 plague bacteria could be detected. A rabbit inoculated with lung tissue died in six 

 days with extensive subcutaneous infiltration on thigh and abdomen, spongy, blood- 

 stained. Spleen somewhat enlarged ; liver with slight coagulation necrosis. Al- 

 though we have here the indications of the presence of both germs, only swine 

 plague bacteria were found in an agar culture from the spleen. 



No. 16, fresh animal. Skin normal ; spleen very large, gorged with blood. Liver 

 normal; both kidneys have the medullary portion almost completely absorbed. 

 Ureters distended to a diameter of one-third to one-half inch. Catarrh of bladder. 

 A few stringy deposits on coils of intestine. Lymphatics of large intestine enlarged, 

 indurated, pale. Stomach normal. In lower ileum one large ulcer 2 inches long 

 and several small ones. Large intestine ulcerated. In caecum the valve is covered 

 with a thin, brick-red slough. Near blind end two button-shaped, flat ulcers, one- 

 half inch across, and a large number of very small ones. In the upper half of colon 

 a few ulcers of similar character. 



Feeble adhesion of both lungs to chest wall, barely collapsed. All but the 

 azygos lobe and a narrow dorsal strip of lung tissue in each lung hepatized. A 

 membranous exudate covers the diseased portion, thicker ventrally easily peeled 

 off. In the right lung the hepatization is dark red, granular. The region of the 

 ventral lobe (middle region) shows dorsally necrotic foci (i. e., lobules, or portions 

 of them, of a homogeneous, pale grayish-yellow appearance, very minutely honey- 

 combed, cutting like cheese, and sharply outlined from the surrounding tissue). 

 The ventral lobe itself below these foci has the air tubes of all sizes filled with case- 

 ous cylindrical plugs. The necrotic centers are numerous in the cephalic lobe. 

 The left lung is in substantially the same condition. Bronchial glands enlarged, 

 firm, pale red. White thrombi in all vessels leading to or from heart. 



In cover-glass preparations from the recently hepatized lung tissue a considerable 

 number of polar-stained bacteria can be seen. A rabbit inoculated from it died in 

 five days, with extensive pasty infiltration of the subcutis; hemorrhagic points on 

 caecum; spleen moderately enlarged. An agar culture from the spleen contains an 

 abundant growth of swine plague bacteria. Through some oversight the results of 

 cultivations from the spleen of this pig were not noted down. 



No. 17, fresh animal. Spleen very large and dark, friable, about 14 inches long, 

 2i wide. Superficial inguinals enlarged, with minute petecchiae on section, and 

 small areas and lines of a pale grayish, waxy cast. Complete loss of medullary sub- 

 stance of both kidneys, due to the formation of cysts varying in diameter from one- 

 half to 1 inch. In left kidney about one-half of cortex also gone; four or five pa- 

 pillae still show on the median section. In the right kidney only one small cyst in 

 cortex. Liver dark, firm to the touch; lobules on ventral surf ace slightly project- 

 ing. On section the center of acini brownish red, the periphery pale. When 

 scraped the parenchyma comes away as a pultaceous mass, leaving a tough honey- 

 combed frame- work (cirrhotic). 



Digestive tract: Mucpsa of fundus of stomach wine red; at periphery of oesopha- 

 geal expansion a blackish patch, three-fourths of an inch across, slightly depressed 

 and covered with islands of yellowish slough. In the cardiac region are numerous 

 erosions from one-sixteenth to one-fourth of an inch across; all covered with a soft, 

 whitish deposit. The mucosa of duodenum has its minute vessels injected and 

 about one small ulcer to a square inch, superficial, with slough stained deep yellow. 

 For 2 feet from the valve the mucosa of ileum contains ulcers varying in size, a few 

 very large, with puckered margin. The caecum, filled with brownish, soft excreta, 

 contains about two dozen ulcers, flattish, center blackish, periphery yellow. The 

 base of these ulcers consists of a neoplastic, whitish, tough tissue. Throughout the 

 colon are small yellowish ulcers, quite superficial, a few even in the rectum. 



Thoracic cavity: Right costal pleura and diaphragm of right side covered by a 

 layer of soft, shreddy material, thickest on the latter. The entire right lung covered 

 with a similar exudate of variable density. The anterior (cephalic) half of this lung 

 hepatized; the hepatization varying from a dark red to a grayish red. The air- 



