KEPOET OF THE BUKEAU.OF ANIMAL IKDUSTEY. 131 



tubes are plugged with translucent and opaque "whitish plugs. At the caudal tip of 

 the principal lobe a group of lobules, solid, grayish, undergoing caseation. The 

 bronchioles are plugged with white curdy masses, and contain remnants of lung 

 worms. Only one-half of the two anterior (ventral and cephalic) lobes of left lung 

 solid. The remainder of lung oedematous. The azygos lobe completely hepatized, 

 the cut surface of a glistening brownish red, with curdy plugs extruded from the 

 bronchioles on pressure. They are made up chiefly of leucocytes (pus cells). Tra- 

 chea and bronchi contain a large amount of a viscid, jelly-like material. 



Bacteriological examination of the pleuritic exudate revealed among leucocytes a 

 large number of very minute cocci ; in some a polar stain is visible. In a few 

 leucocytes the nucleus was situated near one side, and between its two branches the 

 cell protoplasm contained from fifteen to twenty bacteria. A gelatine tube culture 

 made directly from the pleuritic exudate failed to develop. A liquid culture from 

 the same source contained chiefly swine plague bacteria and a few motile hog 

 cholera bacilli. An agar culture was covered on the following day with a very 

 delicate growth containing only swine plague bacteria so far as it could be examined. 

 After four days, however, a denser growth invaded the agar surface from below, 

 made up of hog cholera bacilli. The lung tissue showed the same organisms in 

 large numbers. 



From the spleen only hog cholera bacilli were obtained in a liquid, an agar cult- 

 ure, and a gelatine roll culture in which about two hundred colonies appeared. 



The following notes refer to fresh pigs (excepting No. 12), which 

 were either simply placed in the infected pen or previously fed with 

 viscera of dead swine. They indicate the decline of the swine plague 

 (lung disease) and a still considerable virulence of the hog cholera. 



October 3. No. 12, vaccinated animal, found dead this morning. Pleura! and 

 abdominal cavities contain considerable blood-stained serum. Blood extravasation in 

 muscular tissue of abdomen along median line. Caecum and upper colon filled 

 with small pebbles. Death from injury. A culture from spleen remains sterile. 



October 8. Nos. 39 and 40, fed with viscera of hog cholera cases October 1, dead 

 this morning. In No. 39 the mucosa of ileum and large intestine was necrosed 

 superficially in the form of a thin layer. Lungs, with exception of a small patch 

 of collapse on left ventral lobe one-half inch square, normal. Spleen contains hog 

 cholera bacilli. In No. 40 the lesions were the same. The lungs were normal but 

 contained lung worms. 



October 10. Nos. 1 and 2, fed with viscera of dead pigs September 31, found dead 

 this moring. In both there was extensive necrosis in ileum and large intestine, 

 while the lungs were normal. Cultures from the spleen of No. 2 contain only hog 

 cholera bacilli. 



Nos. 41 and 42 fed together with Nos. 39 and 40, with hog cholera viscera, October 1 ; 

 both dead this morning. In both the mucosa of ileum and large intestine was ne- 

 crosed; the lungs were entirely normal. Cultures from the spleens of both on agar 

 contained only hog cholera bacilli. 



October 15. No. 467, exposed since September 20, found dead this morning. Post 

 mortem changes begun. Thorax and abdomen contain a considerable quantity of 

 bluish-red serum of an offensive odor. Spleen enlarged, congested. Lymphatics 

 of groin hemorrhagic. No ulcers in large intestine, but mucosa highly inflamed. 

 Lungs contain a few hemorrhagic points, otherwise entirely normal. 



October 18. No. 71, exposed October 8, dead this morning. Lungs normal. The 

 lesions are confined to digestive tract. Slight diphtheritic deposit on mucosa of 

 lower ileum. In caecum and colon, the deep wine-red mucosa is studded with a large 

 number of small ulcers. Culture on agar from spleen contains only hog cholera 

 colonies. 



October 19. No. 73, exposed October 8, dead this morning. Spleen enlarged and 

 lymphatics generally hemorrhagic. Lungs contain numerous hemorrhagic centers 

 from one to four lines across. In each ventral lobe a small region collapsed ; no 

 hepatization. Kidneys contain hemorrhagic points. Extensive ulceration of caecum 

 and colon. Culture from spleen contains hog cholera bacilli. 



October 21. No. 74, fed with viscera from diseased pigs October 13, died this 

 morning. Extensive ulceration in both large and small intestines. Spleen engorged. 

 Lungs normal. 



October 22. No. 72, exposed October 8, dead this morning. In this case we again 

 meet with lung disease. Lung small. Left lung roughened on the entire surface, 

 condensing in some places into a delicate mesh-work. The lesser half of principal, 

 the whole of ventral, and portion of cephalic lobe airless. In the principal lobe the 

 hepatization varies from a catarrhal plugging of air tubes and alveoli, near the 



