146 EEPOET OF THE BUEEAU OF ANIMAL INDUSTEY. 



exudate, very few in blood and spleen. An agar culture from the blood fertile. 

 In all respects the germ is identical with that of swine plague. 



A rabbit inoculated from the agar culture of the first rabbit indirectly, by inject- 

 ing subcutaneously ^V cubic centimeter of a bouillon peptone culture made from it 

 died in four days with substantially the same lesions, excepting that the thigh mus- 

 cles were more extensively discolored. 



The second rabbit inoculated from the lung tissue of the pig died in eight days. 

 The lesions of this animal were of the same character but less severe. The hemor- 

 rhages on the intestines were absent, though the exudate was abundant. From the 

 blood two agar tubes were inoculated; both developed an abundant growth of the 

 same bacteria (swine plague) obtained from the first rabbit. 



The condition of the second pig when killed was like that of the first. The ab- 

 dominal organs were normal. The lungs were free from adhesions. Throughout 

 all the lobes of both, but especially along the margins of principal lobes, are masses 

 about the size of a marble, or in the form of a thin layer under the pleura, of a 

 waxy, semi-translucent aspect, on section solid. The remainder of the lung tissue 

 cedematous. 



Two rabbits were inoculated from lung tissue. Of these, one died on the fourth 

 day. There were no lesions to account for death; no germs in the various cultures 

 from its organs. The second rabbit remained well. 



From the spleen of each pig three agar tubes were infected with bits of spleen tis- 

 sue. The three cultures made from the second pig remained sterile. Two from the 

 first also remained sterile. In the third tube a germ like swine plague appeared 

 which failed to develop when transferred to fresh tubes. 



It is highly probable that the outbreak was swine plague, although 

 the presence of swine plague germs in one case can not be regarded 

 as conclusive evidence. It is remarkable that these germs should 

 still be present in an animal almost recovered from the disease. 



Maryland. The cases reported below were very likely affected 

 with hog cholera, although the bacteriological examination, as far 

 as it went, gave negative results. It seems reasonable to suppose 

 that when swine roam over a considerable extent of territory in 

 search of food the virus is more widely distributed but less concen- 

 trated. Less virus is therefore taken up by individual animals, 

 and although the disease is equally fatal in the end, the course may 

 be somewhat different and the lesions less extensive. At the same 

 time the bacteria may elude observation. They may remain more 

 or less localized, owing to the reactive power of the organism, which 

 destroys those that have entered the internal organs. To those who 

 would give up the search for hog cholera bacilli after a few unsuc- 

 cessful attempts to find them we would recommend the perusal of 

 the following three cases: 



Swine diseases prevailed more or less in Montgomery County, Md. , during the 

 latter weeks of September and the early part of October, 1888. 



October 17. Mr. H lost about twenty-two out of a herd of fifty-five to sixty 



swine during the past four weeks. Of those now scattered in a large field two ap- 

 pear ill ; one, a small black shoat, is killed by cutting its throat, and examined. 

 The superficial inguinal glands are very much enlarged, the surface mottled, dark 

 red ; the spleen large, but pale and rather firm. The liver shows signs of invasion 

 of the Sclerostoma pinguicola. The lymphatic glands at lesser curvature of stom- 

 ach are very large ; cortex completely hemorrhagic. 



The left lung normal ; the principal lobe of the right lung has in it a mass of tis- 

 sue involved in broncho-pneumonia, extending obliquely from the free border to 

 near the dorsal region, about 1 inch thick. The lymphatics along the dorsal aorta 

 are likewise hemorrhagic ; the stomach filled with food ; small intestines contain a 

 number of attached echinorhynchi ; the large intestines distended with semi-solid 

 fecal matter. The mucosa, in general, is normal, but in the caecum are two ulcers 

 about three-eighths of an inch across, round, slightly elevated, with center black 

 and periphery yellow. Beneath the superficial slough is a whitish, firm, new 

 growth, extending to the muscular coat in the center of the ulcer. 



The spleen and the right lung were taken to the laboratory. From the former 

 cultures were made on agar, in gelatine and beef infusion, by adding bits of spleen 

 tissue as large as peas. In no tube did any development take place. A rabbit in- 



