IlfcPORT ON DOtTRINB. 9 



Mare V. New Zealand mare, covered twice within 43 hours 

 by Yadffir, and Arab stallion, the subject of Dourine, exhibiting 

 a sore on the anterior superior surface of the free portion of the penis. 

 Vesicular eruption, ulcers on labia vaginae followed by leucodermic 

 patches. Swelling and cadema of external genitals and perineum, 

 latter tissue around anus involved. Vaginitis and mucopurulent dis- 

 charge. Appearance of the trypanosoma in the blood obtained from 

 vaginal petechise. Absence of the protozoon from vaginal mucus 

 during the whole course of the disease. Complete absence of cuta- 

 neous plaques, urticaria or eruption of any kind. Symptoms of para- 

 plegia developed suddenly, inability to stand. Death. Post-mortem. 



Mare VI. Country-bred mare covered by Arab stallion 

 Monarch) subject of Dourine, during early period of eruption of 

 cutaneous manifestation, but absence of sores from penis. No 

 eruptions of vesicles or other eruptions implicating vulva or vaginal 

 m. m. First plaque appeared on 31st day following primary cover- 

 ing (trypanosoma), followed at irregular intervals by successiw crops 

 of plaques, which involved the skin of the body and neck principally. 

 Thickening of labia-pudendi, followed by oedema of udder and later 

 by oedema on under-surface of abdomen. Absence of leucedermic 

 patches implicating tissues of vulva, anus, and udder, as also of nerv- 

 ous symptoms up to the 235th day after covering, with the excep- 

 tion of stiffness of the right hind limb. 



Mare VII. Country-bred mare covered by Arab stallion 

 Monarch, the subject of recent Dourine. Appearance of Vesicular 

 Exanthema (coital), later followed by leucoderma of the cutaneous 

 parts affected. Eruption of first plaque on the 24th day after cover- 

 ing. Presence of trypanosoma in blood drawn from first plaque. 

 Eruption of ten plaques in all during 160 days. Presence of the 

 trypanosoma in blood drawn from first plaque. Eruption of ten 

 plaques in all during 160 days. Presence of the trypanosoma in 

 vaginal mucous on the 50th day and persistence at intervals during 

 whole course of observation lasting 8 months. Absence of weakness 

 across the loins or other cerebro-spinal complications up to the 

 230tb day after primary covering. 



Mare VIII. Country-bred mare covered by Arab stallion 

 Monarch, the subject of recent Dourine. Appearance of Vesicular 



