REPORT ON DOURINE. 



Exanthema (coital), later followed by leucoderma of , the exter- 

 nal affected parts . Eruption of first cutaneous plaque on thirty- 

 third day after covering (trypanosoma discovered), followed during 

 ensuing three and half months by 18 similar patches. Vaginal 

 mucus contained trypanosomata in large numbers on the 17th day 

 and at varying intervals up to 4 months after eruption of last 

 plaque. Absence of cerebro-spinal complications up to 212th day 

 after covering. 



Monarch, a bay Arab stallion, age 5j years, 14-1^, was landed 

 in Bombay in November, and received at Babugarh on 2nd Dec- 

 ember 1902. .The animal was cast for cataract on the 29th and 

 received at the Imperial Bacteriological Laboratory at Bareilly on 

 the 31st March 1903. This horse was allowed to cover mare No. Ill 

 on the 4th-7th May, the latter animal having been inoculated 

 eighteen days previously on the m. m. of the left labium-pudendi 

 with a slight trace of blood, drawn from a cutaneous plaque on 

 Kilngarth (spontaneous Dourine). At the time of covering the 

 mare presented swelling of left labium, and the trypanosoma was 

 discovered in small numbers in the vaginal mucus. The first im- 

 portant symptom exhibited by Monarch, viz., thickening of the 

 sheath, appeared on the 3rd June and was followed by the eruption 

 of plaques on the 6th ; from this latter date until the 15th February 

 1904 a succession of subcutaneous plaques made their appearance 

 during the interval of nearly 9 months, while concurrently the 

 general manifestations of Dourine were respectively observed. 

 During the tarly part of the month of February 1904 the animal 

 suffered from malaise and frequently assumed the recumbent posi- 

 tion during the day-time. On the 20th porter-coloured urine was 

 passed on one occasion only and red blood corpuscles found m the 

 sediment on microscopical examination. On the 25th there was 

 gome weakness in the hind quarters, but this was only noticeable 

 on the removal of the animal from its stall, the first thing in the 

 morning. Continued pressure over the lumbar region made the 

 animal crouch and almost fall to the ground. 



Donkey III. A small entire country-bred, aged 3| years, re- 

 ceived at Muktesar from Bareilly district on 31st July 1903. 

 Body temperature varied between 37*6C. and 98'0C. during 



