16 



REPORT ON DOURINE, 



While in mare No. VI tumefaction of the vulva followed 24 

 hours after the eruption of the first plaque, and in mare No. V, 

 although the submaxillary glands were enlarged and on the 49th 

 day increased swelling and cedema of the labia occurred, there was a 

 total absence of plaques. 



When Coital Exanthema makes its appearance in mares, it is 

 next to impossible to make any certain diagnosis with regard to the 

 presence of Dourine until the primary disease has run its course 

 and disappeared, or until the trypanosoma has made its appearance 

 in the vaginal mucus. In stallions, unless attention is directed to 

 an abnormal condition of the free portion of the penis or to that of 

 the meatus-urinarius, it is more than probable that the first symp- 

 tom to attract attention will be the thickened condition of the 

 sheath, which may be absent one evening but manifest on the fol- 

 lowing morning. 



TABLE I 



Showing the length of the period of inoculation in experimental 

 animals, that is the period which elapsed between the first 

 covering or inoculation, and the primary symptom referable to 

 Dourine. 



