80 REPORT ON DOURINE. 



During the act of micturition the lower part of the vaginal passage 

 was washed free of mucus, so that, if an attempt were made imme- 

 diately after the act, no mucus was forthcoming. It was observed 

 that the eruption of plaques frequently made their appearance 

 during the periods of intermission, or absence of the trypanosoma 

 from the vaginal mucus, but exceptions to this were noted in mare 

 IV, in which the trypanosoma was only discovered in the mucus 

 on the 289th day after covering, and in that of mare I the proto- 

 zoon was not found at all. 



(X) Exciting causes which frequently bring about a primary 

 or a further eruption of plaques. The course of Dourine in some 

 horses is particularly noticeable on account of the small number of 

 plaques which make their appearance ; consequently there is a long 

 period of intermission between their respective eruptions. In others 

 certain stallions exhibit latent symptoms only, such as swelling of 

 the sheath for long periods, but no other signs of the disease. In 

 these two classes of cases it has been found that, if the animals are 

 subjected to certain depressing conditions, principally brought 

 about by fatigue from whatever cause, such as covering, shaking 

 during a long railway journey, prolonged march, or throwing .and 

 bleeding an animal to the amount of 20 c.c. from the jugular vein, 

 a fresh eruption, or, as in the second instance, a primary eruption 

 of plaques, may become manifest within a short period. The follow- 

 ing examples may be given in illustration of the first class of cases. 

 Yadgir. Plaque 31- appeared 25th October 1903. On the 

 15th December 1903, 51 days had supervened without the erup- 

 tion of a plaque. Bled 20 c.c. on latter date. Plaque No. 32 

 appeared 60 hours after bleeding operation. 



Shamsher. Plaque No. 17 appeared on 29th September 1903. 

 December 16th, 1903, 78 days supervened without the eruption of 

 a plaque. Bled 21 c.c. on latter date. Plaque No. 1 8 appeared 

 36 to 40 hours after the bleeding operation. 



The following instance may be given in support of the latter 

 class of cases : 



Yadgir. Swelling of sheath and scrotum reported in August 

 1902 ; no other symptom noted nntil animal despatched by train to 

 Bareilly on the 29t)i and arrived on the 31st March 1903. First 



