REPORT ON 



cutaneous lesions of vago-neurotic origin are developed. In addition, 

 slight or more pronounced complications with regard to nutrition, 

 momentary or more persistent paralysis, an abnormal sensibility of 

 the lumbar region, kidney-complications, spasmodic affection or loss 

 of control over the movements of the hind limbs while walking, and 

 sudden flexion of the fetlock joints may become apparent. 



The cutaneous manifestations may be divided into three varie- 

 ties of eruptions : 



(i) The plaques or patches, the most generally marked symp- 

 tom of Dourine (blood of which contains the trypano- 

 soma), but which are not absolutely pathognomonic of 

 the disease, as an animal may pass through an attack 

 and eventually succumb to paralysis and the trypano- 

 soma be demonstrated in other fluids, without the 

 animal exhibiting any cutaneous symptom, 

 (ii) Disseminated urticaria more or less of a fugitive character. 

 (Hi) Eruption of small vesicles. 



(1) Plaques. These are elevations which may appear suddenly 

 or slowly ; earlier as a rule in mares than in stallions, when the 

 disease is contracted spontaneously. Developing on any part of the 

 body including the upper portions of the extremities, these plaques 

 are neither hot nor tender on manipulation. They appear singly or 

 in crops at successive intervals, so that during their eruption the 

 course of the disease is marked and in some cases sharply defined 

 by the presence of paroxysms and intermissions as in the case of 

 Surra. The number of plaques which may appear vary consider- 

 ably during each paroxysm, and the length of both paroxysms and 

 intermissions are also subject to great variation in the same and 

 different animals. The plaques vary from half an inch to eight 

 inches in length. In this country according to our observations 

 they appeared in the majority of instances in mares and in a few 

 stallions from the 24th to the 34th day after the first covering or 

 inoculation, while in the majority of stallions they appeaired at a 

 much later date. 



The different forms assumed by the plaques are 

 (i) The classical plaque observed in Europe and North Africa 

 is as if a tljin disc of metal had been introduced under 



