1! I. PORT ON DOUR1M 37 



reduce the strength of the animal and bring about death prema- 

 turely. The temperature during this phase of the disease, unless 

 in the presence of severe complications, continues to run an even 

 course, scarcely varying between a minimum of 37 and a maxi- 

 mum of 38 C. 



III. Phase. In acute cases of disease in the stallion and mare 

 the general symptoms gradually become aggravated ; there is pro- 

 gressive emaciation together with marked weakness and anaemia. 

 The animal, whose hind limbs scarcely appear to belong to its body, 

 has difficulty in maintaining the upright position. Paraplegia at 

 this stage may appear suddenly, without any previous indication, 

 and the animal thus stricken is unable to rise, and although able 

 to take food in the recumbent position, dies within a few days from 

 exhaustion, or from lung complications. On the other hand, 

 although greatly emaciated animals presenting symptoms of mus- 

 cular paresis or paraplegia have been observed to fall and be unablo 

 to regain the upright position without assistance, nevertheless all 

 such cases are not hopeless, for some may gradually improve and 

 lose all signs of weakness in the loins and limbs and again proceed 

 to put on flesh. 



As the disease advances, it will be found that, as in the course 

 of Surra in equines, so in Dourine the quantity of urea is greatly 

 increased to twice or thrice the normal output. Towards the ter- 

 mination of an acute case hromaturia or hsemoglobinuria may 

 supervene. In the former case the urine is thick, reduced in quan- 

 tity, presenting the appearance of porter, the amount of salts is 

 increased, and a small percentage of albumen is present. In addi- 

 tion, at this stage the urine is laden with granular casts, giving 

 an indication of the severe changes which have implicated the 

 kidney structures. Until a few days before death, the body tem- 

 perature may have never exceeded normal limits and even at death 

 the temperature may register but 38'5 C. On the other hand, 

 fever may gradually supervene within the last few days of life and a 

 maximum temperature of 40'5 be present when death takes place. 



Dourine in the ass. The symptoms of spontaneous Dourine 

 in the ass are few and discrete and in the ordinary course of events 

 would be overlooked, unless, as occasionally happens, there is an 



