4g REPORT ON DOTTRINE. 



Section IX PATHOLOGICAL ANATOMY. 



The course of Dourine is essentially chronic in character except 

 in a very small percentage of cases, consequently in those animals 

 which succumb to the disease the body is usually emaciated, for, 

 as in the case of Surra in equines, this malady is characterized by 

 a progressive emaciation or loss of flesh, particularly noticeable in 

 the region of the croup, hips, and loins. Should the animal suc- 

 cumb during the eruption of cutaneous plaques, certain circum- 

 scribed elevations may be noticeable on the surface of the body. 

 In stallions, the penis will be seen to be partially protruded from 

 the sheath and infiltrated more or less towards its free extremity, 

 the external surface of the mucous-membrane may exhibit small 

 round cical rices white in colour, the sequelae of former ulcers. 



The urethral mucous-membrane is usually protruded and some- 

 what thickened. The proportions of the sheath vary much in 

 different cases, from little or no increase to large dimensions. On 

 section of such a sheath, the structures will be seen to be indurated 

 and considerably thickened and at the same time to be distended 

 with gelatinous material through which fibres of connective tissue 

 cross and recross, thus binding the btructures together. In the 

 mare, the anus will be seen to be retracted, lying at the anterior 

 extremity of a cavern-like depression, the lips of the vulva patent 

 in the lower commissure, either somewhat cedematous or atrophied 

 in emaciated animals, and sometimes the seat of leueodermic 

 patches. 



On removal of the skin, a thin film of gelatinous material, 

 together with discolouration of the tissues at the seat where the 

 plaques were situated, will probably be all the signs noted, except 

 in such animals as have exhibited more or less oedema on the most 

 dependent parts of the body, viz., chest, abdomen and lower ex- 

 tremities. In some cases, this material may assume inordinate 

 proportions in such situations. In small quantities this gelatinous 

 exudation may be found between the muscles and running along 

 the sheaths of the large nerve trunks. On opening up the body, 

 it may be observed that the muscles are atrophied more especially 

 in those regions above noted, and on microscopical examination it 



