50 



REPORT ON DODRINB. 



lesions. The most important changes are observed in the spinal 

 cord, more especially in the lumbar and sacral portions. The cere- 

 bro-spinal membranes may be thickened in a minority of cases, 

 but the fluid which they contain is nearly always increased and 

 may present a normal, opalescent, or reddish colour according to 

 the degree of changes present. It collects more especially at 

 the bracbial and lumbar enlargements. The cord in advanced 

 cases of disease is attenuated in different situations, and on trans- 

 verse section it presents an asymmetrical appearance, the tissues 

 may be softened and permeated with red spots or almost fluid in 

 localized areas. The grey matter is atrophied. The posterior 

 columns of the cord appear to be the ones which are principally 

 involved in the course of Dourine, and according to Marck, the 

 change observed in the nerves is a poly-neuritis. 



TABLE VIII 



Showing the pathological conditions found in animals which succumbed to 



Dourine. 



