REPORT on DOURINB. 



for the first time on the free portion of the penis of the horse ; 

 the organ, however, was not noticed to be abnormally enlarged or 

 discoloured. "Within a period of twenty-four hours after the last 

 covering, symptoms of vaginitis had made their appearance. The 

 external surface of the vulva, the inner surface of the labia pudendi 

 and the vaginal m. m. presented vesicles in different stages of 

 development. The symptoms of vesicular exanthema affected the 

 external and internal tissues concurrently, but may here be described 

 separately. The external manifestations on the vulva were first 

 observed 18 hours after the last covering, when vesicles were noted 

 to be dotted over the outer surface of the labia pudendi. Twenty- 

 four hours later, the eruption of vesicles had considerably increased 

 and implicated the surrounding parts in close proximity to those 

 previously affected. 



On the 6th July, each individual vesicle appeared upon a raised 

 and swollen base, some more marked than others, the contents of 

 which were then becoming opaque and of a yellowish tinge ; later 

 all formed pustules, which more or less persisted from the 7th to 

 the llth inclusive. On the morning of the 12th most of the con- 

 tents of the pustules had become evacuated and open sores or ulcers 

 remained in their place. Twenty-four hours later, the process of 

 healing commenced and was maintained under scabs until 

 morning of the 17th, when some of the latter separated and fell off, 

 leaving patches of leucoderma according to the area of the tissues 

 involved in the inflammatory changes. Between the 18th and 

 22nd, the healing process continued and was completed by the latter 

 date. The primary symptoms of the 4th July affecting the vagina, 

 as before stated, consisted of an eruption of vesicles on a highly 

 inflamed m. m. Within 24 hours the maximum eruption of vesicles 

 had taken place, and some had already formed superficial ulcers, a 

 form which all assumed later by the same evening. From the 6th 

 to the 13th the ulcers remained patent, probably on account of the 

 muco-purulent discharge which appeared on the 10th and persisted 

 for 48 hours, when its place was taken by a sero-sanguinous dis- 

 charge on the 1 2th which made its escape from the vaginal orifice, 

 but it had totally disappeared on the morning of the 3 1st. The 

 process of healing set in during the 14-th and all ulcers had healed 



