70 



HEP OUT ON DO U BINS. 



by the following day. The vaginal discharge ceased on the 2nd 

 August. 



Mare Fill. A country-bred; aged 3 years, was covered by an 

 Arab stallion Monarch at noon on the 5th July 1903. At the 

 time of serving numerous small ulcers existed on'the m. m. of the 

 fres portion of the penis. On the morning of 6th July, 19 hours 

 after covering, vesicles had already appeared on the inner surface 

 of tbe labia pudendi and on the vaginal m. m. On the 7th and 8th, 

 the vaginal m. m. presented a deep-red colour and numerous small 

 ulcers existed over its surface and a muco-purulent discharge escaped 

 from the passage. On the 9th, a second series of symptoms 

 appeared complicating the vulva and tissues situated externally. 



(a) From the 9th to the 17th inclusive, the vaginal symptoms 

 increased in severity, and between the 18th and 20th, some of the 

 ulcers on the m. m, healed. On the 21st, the trypanosoma was 

 observed for the first time in the vaginal mucus, the muco-purulent 

 discharge was on this date intermittent in its appearance, for the 

 most part being only observed in the morning and evening. 

 Twenty-four hours later petechise appeared on the m. m. and per- 

 sisted for several days ; they then faded and finally disappeared on 

 the 23rd, and by the morning of the 26th all ulcers on the m. m. 

 had healed. 



(b) The external manifestations above referred to were first 

 observed on the morning of the 9th, when vesicles and pustules 

 raised above the surface of the surrounding tissues, both discrete 

 and confluent, were found on the vulva and tissues surrounding the 

 part. During the next 48 hours fresh vesicles and pustules 

 formed, while the ones which previously existed developed into 

 ulcers, and from the 12th to the 15th, the evolutionary process 

 continued, some ulcers healing whilst fresh ones formed. During 

 the 16th and 17th, the condition appeared to remain stationary, but 

 from this latter date healing proceeded without interruption. On 

 the 31st July, the vulva became thickened and generally enlarged, 

 and on the following day numerous black film-like scales became 

 denuded, leaving eight patches of leucoderma. 



