74 REPORT ON DOURINE. 



presenting a eore at the time of covering, both mares covered by this 

 horse suffered from Vesicular Exanthema, although previous to the 

 appearance of the sore no symptoms followed in the mare. It 

 would appear, therefore, that another organism developed in the 

 sores which produced the secondary infection, for no trypanosomata 

 or their developmental forms were discovered in fresh or stained 

 specimens of material from the sores. 



As a diagnostic symptom, what deductions can be drawn from 

 the presence on the external genital organs of non-congenital areas 

 of leucoderma ? 



There is no doubt that any form of inflammation, if sufficiently 

 severe affecting the cutaneous tissues of the external genital organs 

 and those in close proximity, will bring about changes which, when 

 the healing process has concluded its task, will leave unpigmented 

 areas of patches of leucoderma. It has been demonstrated during 

 the course of the two maladies, Vesicular Exanthema and Douriue, 

 that each is accompanied by a sufficiently severe form of inflam- 

 mation to produce the above changes. When leucoderma which is 

 not congenital is present in an animal, stallion or mare, it should 

 therefore be regarded with suspicion, and every needful precaution 

 exercised. In the present state of our knowledge we cannot say 

 more than that in countries where the two diseases are enzootic, in 

 all probability, the animal ha s passed through an attack of Vesi- 

 cular Exanthema or one of Dourine, most likely the former. For 

 if the animal is in good condition and apparent health, it would 

 point to the fact that the previous disease had been Vesicular 

 Exanthema, for during the course of the latter disease 70 per cent. 

 are said to succumb to the malady, and but a small percentage of 

 the remainder would ever regain perfect health and condition. 



Section XIII PYROPLASMOSIS. 



In the bovine, equine, ovine, and canine species, diseases bav0 

 been described in "one or other paits of the world which differ 

 somewhat, but which in a percentage of cases are associated with 

 hsematuria or with hasmo-globinuria j the ' materies morbi ' 

 being in each instance a form of Pyroplasma. The disease 

 presented by each species of animal respectively is more or less, 



