APPENDIX. XVii 



VENDOR. 



Horse used for stud purposes in the district . Received at Depot for summer 

 rest (July 1901), suffering from debility, loss of weight, enlargement of 

 scrotum and sheath, swelling of kind limbs. Treatment, Iodide of Iron 

 and Nux Vomica, regular exercise. Apparent recovery. Used for stud 

 purposes from October 1901 to July 1902. On return to depot presented 

 symptoms of advanced Dourine. Treatment, Mercuric Perchloride and 

 Potassium Iodide. General improvement and recovery conjectured, showed 

 no symptoms of ill-health during period of 10 months. June 1903 covered 

 mare suffering from Dourine, followed 18 days later by eruption ofcuta- 

 neous plaque (trypanosoma) and during 12 weeks, by 17 further plaques 

 together with disseminated urticaria. (Edema of throat extending to 

 chest, weakness and later, loss of power over hind quarters, hamoglo- 

 binuria and death. 



A thorough-bred Australian horse, aged, received from Babugarh Remount 

 Dep6t on the 31st March 1903, with the following history : 



1st July 19D1. This animal was received in this Dep6t for summer rest 

 and it was then observed that it had not only lost considerably in weight and 

 looked bony but had a distinct enlargement [of the scrotum and sheath and 

 that the hind limbs were swollen. The treatment adopted was brisk purgative 

 followed by internal administration of Iodide of Iron and Nux Vomica in the 

 form of a bolus, regular exercise, which, if neglected, caused the animal's ex- 

 tremities to swell more, so that exercise reduced the swelling of the sheath, and 

 the scrotum appeared smaller. In October 1901 the animal was again sent 

 out to the district and no more was heard of it until 1st July 1902. This time 

 a further reduction in condition was observed and the animal showed apparent 

 weakness about the loins, the sheath and scrotum were more enlarged, but the 

 swelling of the hind limbs was less. Further, there was an eruption of,circ-nlar 

 patches at intervals. The animal was then treated with Liquor Arsenicalis and 

 Tinctuva Nucis Vomica), but finding no decided change for the better under this 

 course, the following was substituted, viz., Liquor Hyd. Perchlor. Potass 

 Chlr. and Potass Iodide in the form of a drench. This seemed to have had 

 the effect of checking the eruption'of circular patch e.s as no fresh ones appeared ; 

 the horse fed well, showed no symptom of ill health and gained considerably 

 in weight by October 1st, 1902. Between this latter date and March 31st, 1903, 

 the only symptom visible was some thickening of the sheath and scrotum. 

 On April 10th the animal was removed up to the Muktesar Laboratory (eleva- 

 tion 7,500 ft.) and from the date of its arrival until June 23rd, there was not a 

 degree difference between the morning and evening rectal temperature, which 

 only varied between 37 and 38 C. On this latter date and on several occasions 

 within the next few days, the animal was allowed to cover mare No. 1 in order 

 to observe whether Vendor was susceptible to the disease, for although no 

 trypanosouiata had ever been discovered in the vaginal secretion, nevertheless a 

 number of unmistakable plaques had appeared on the cutaneous surface of the 

 body of the mare. 



June 30th. Considerable swelling and codema of the sheath occurred which 

 later developed into a paraphymosis which was only partially reduced by 



