APPENDIX. llv 



MARE III. 



Scarification of minute portion of mucous-membrane of left labium vagina, 

 with a needle, and inoculation of trace of fresh, blood obtained from a 

 Dourine plaque on English thorough-bred ttalHon Kilngartli Appear- 

 ance on 12th day of vesicle followed by a small ulcer, which readily 

 healed^ Swelling and oedema of L. labium, which later involved whole 

 external genitals and perincrum Vaginal mucut contained the try- 

 panoxoma of Dourine -First plaque appeared on 34th day following 

 inoculation, in the blood of which the trypanosomata were found on 

 microscopical examination, followed at intervals during a period of 117 

 days by successive crops of plaques, numbering 80 in all, which involved 

 t Jtr skin of the body and neck. Slight enlargement of the submajrillary 

 glands Weakneses, later dragging of the hind limbs whilst walking^ 

 Swelling and suppuration of near liind limb Inability to stand 

 Destruction Post-mortem Course of the disease 206 days. 



A bay Australian mare foaled in 1896, purchased 29th November 1901, 

 15-2 } hands, was cast from the Government Remount Depot, Karnal (No. 6601 ), 

 a* a bad roarer, on the 7th March 1903. The animal when received at Bareilly 

 was in good condition ; the temp, during the following month always re- 

 mained between 37 and 38 C. 



April 17th t 1903. Scarification with a fine needle was performed involving 

 0*5 c. m. square of the mucous-membrane of the left labinm vagina) in such a 

 way as to draw little or no blood. A slight trace of blood was removed from a 

 Dourine p'aque from Kilngarth (thorough-bred English stallion) on the point 

 of a scalpel and spread over the scarified m. m. and allowed to dry somewhat 

 before the parls were brought in apposition. Between the 18th and 28th April 

 inclusive, the animal fed well and exhibited no untoward symptoms. The 

 morning and evening temperatures varied but a few points, the maximum and 

 minimum readings being 38*1I.C. and 37'1 C. respectively. The pulse and 

 respirations averaged 36 and 12 respectively. 



27th. The vaginal m. m. at the site of scarification is congested. Temp. 

 A.M. 37-4 C., P. 30, R. 10 ; P.M. 38" 1 C., P. 3-1, R. 12. 



28th. A vesicle has appeared on the vaginal m.m. at the point of scarifica- 

 tion. The left labium is swollen and cedematous. Temp. A.M. 39*1 C., P. 34, 

 R. 11 ; P.M. 38-3 C., P. 32, R. 13. 



29th. The left l.ibium has increased in size and the vesicle is larger than 

 yesterday. Temp. A.M. 37'8 8 C., P. 32, R. 10 ; P.M. 37'6 C., P. 40, R. 14. 



30lh. The left labium has increased in size since last noted and a small 

 ulcer has appeared at the site of the vesicle. Temp. A.M. 38'0 C., P. P6, 

 R. 12 ; P. M. 38-5 C., P. 36, R. 12. 



May Ist.Tho swelling and cede ma of the left labium has increased still 

 more in size since yesterday : there is no vaginal discharge. Temp. A.M. 

 37-9 C., P. 34, R. 12 ; P.M. S8'l C., P. 44, R. 12. 



2nd. Swelling of the loft labium has decreased, but the cedema is extending 

 downwards towards the perinaoum. Temp. A.M. 37*8 C., P. 42, R. 12 ; P.M. 

 38-3 C., P. 42, R. 16. 



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