APPENDIX. 



MARE V. 



New Zealand mare, covered, twice within 48 hours by YadgJr, an Arab 

 stallioi the sub/eot of Dourine, exhibiting a, sore on the anterior 

 superior surface of the free portion of the penis "Vesicular eruption, ulcers 

 on labia vaginae followed by leucodermic patches Swelling and cedema 

 of external genitals and perinaeum, later tissue around anus involved. 



Vaginitis and muco-purulent discharge Appearance of the trypanosoma 

 in the blood obtained from the vaginal petechice Absence of the pro- 

 tozoan from vaginal mucus during the whole courses of the disease Com- 

 plete absence of cutaneous plaques, urticaria or eruption of any kind 

 Symptoms of paraplegia developed suddenly, inability to sland Death 

 Post-atortem. 



A bay New Zealand mare, 14 >3| hands, foaled in 1897, was cast^ from 

 the Government Remount Depot, Karnal, on the 7th March 1903 as incur able 

 suffering from ringbone 83 days, P. C. lame, near eye-ball ruptured. Daring 

 the period which elapsed between the receipt of the animal from Karnal and 

 the llth May 1903, the temperature never fell below 37 or rose above 38 G. 



The mare was covered on two occasions, viz., llth and 13th May 1903, 

 by Yadgir, an Arab horse suffering from Dourine, which presented a small 

 sore on the anterior and superior surface of the free portion of the penis. 



A vesicular eruption appeared on the external genital organs of the mare 

 on the 21st May which on the 23rd formed ulcers, from which a sticky, 

 viscid fluid exuded which dried and formed a film resembling a thin coating of 

 collodion, over the surface of each individual ulcer. Marked swelling and 

 oadema of the external genitals followed. The primary symptoms persisted 

 until the oth June when the dry film commenced to loosen at their edges and 

 later to separate, they then disclosed patches destitute of pigment (leucoderma) 

 on the site previously occupied by each ulcer. All the films had separated by 

 the llth, and the labia presented a pie-bald appearance. On the 10th June 

 the swelling and cedema of the vulva had slightly decreased in amount and pro- 

 gress in this direction continued until the 19th, when the above symptoms 

 became stationary and the vaginal m. m. assumed a bright red colour, bat 

 there was no discharge from the passage. On the 22nd June, the sub-maxillary 

 glands which up to this date had maintained their normal size, then became 

 enlarged and hard on palpation. Increased swelling and cedema of the labia 

 occurred on the 28th, and on the 29th a little semi-opaque viscid fluid escaped 

 from the vagina on one occasion only. Microscopical examination of the 

 fluid gave a negative result with regard to the presence of the trypanosoma. 

 The swelling and oedema gradually increased and the tissues of the perinseum 

 became infiltrated on the morning of July 3rd. On the 5th of the same month 

 a muco-purulent discharge emanating^from the vagina commenced to escape, 

 but in this fluid no trypanosomata were discovered. The flow continued un- 

 interruptedly until the 12th, when it ceased. During this interval the oedema 

 involving the perinseam gradually decreased and finally disappeared on the 

 10th, but the swelling and oedema of the external genitals remained stationary 

 until the 15th July, when the tissues around the anus became implicated and 



