APPENDIX. hxiii 



assumed a size twice their normal proportions. Swelling of the near hind 

 fetlool- was observed on the morning of the 17th. The animal which up to the 

 19th July had always taken its food well, and had presented no weakness in the 

 hind limbs, on the morning of the 20th was found lying down off feed, dull, 

 and when rai-ed with assistance into the erect portion was found to hare lost 

 power over the hind quarters and WHS unable to stand. Temp. A. u 38*4 C.> 

 P. 64, K. 24. 



Swelling and oedema of the external genitals involving the tissues around 

 the anus were present, the vaginal m. m. exhibited a number of small petechite 

 and microscopical specimens of the blood obtained from them exhibited as many 

 as 14 trypanoeomata in one cover-glass. For the next two days 21st and 22nd 

 the animal fed but only slowly in the recumbent position. The swelling and 

 oedema increased and became infiltrated to the perinteum and thighs, at the 

 same time the vaginal peteohiie persisted. The temperature rose to 39 C., 

 P, 80, H. 30. On the day previous to that on which death occurred, the'cedemu 

 involving the tissues of the anus and external genital orgai.s decreased in 

 amount, but increased over the perinaum, while the temperature rose to 

 39-9 C., P. 88, K. 46. The animal succumbed on the morning of the 24th 

 July. 



AUTOPSY, shortly after death. Presence of yellow- coloured gelatinous 

 infiltration under the skin of chest, perinreurn, etc. 



Lungi. Both organs present a few sub-pleural petechiffl dotted over their 

 surfaces. Slight emphysema of apices. 



Pericardial sac contains 50 c.c. of a dirty yellow coloured fluid. 

 Heart. Sub-endocardial extravasations in left ventricle, otherwise normal 

 in appearance. Liver appears enlarged. Spleen lissues firm, normal in size. 

 Kidney*. Yellow gelatinous material in the hilum of both organs, tissues 

 present healthy appearance. 



Large and small intestines. Deposition of yellow coloured gelatinous 

 material on the external surfaces, especially along the course of the intestinal 

 bands on the former. 



Spinal cord. Membranes contain a tmall quantity of clear fluid. The 

 capillary vestels lying upon the superior and inferior surfaces of the posterior 

 dorsal and lumbar portions of the cord are injected with dark-coloured blood. 



On Section. No centres of softening are visible to the naked eye. Gtiref ul 

 microscopical examination of specimens from the fresh cord failed to reveal the 

 presence of the mature trypanosoma in any portion of it, and similar results 

 were noted with regard to the examination of the cerebro-si inal fluid. 



