1XXX APPENDIX. 



MARE VII. 



Country-bred mare covered by Arab stallion Monarch, the subject of recent 



plaque Dourine. Appearance of Vesicular Exanthema (coital], later 



followed by leucoderma of the cutaneous parts affected. Eruption of first 



on the twenty -fourth day after covering. Presence of trypanosoma in 



blood drawn from first plaque. Eruption of ten plaques in all during 160 



days. Presence of the trypanosoma in vaginal mucus on the 50th day 



and persistence at intervals during whole course of observation lasting 8 



months. Absence of weakness across the loins or other cerebro-spinal 



complications up to the 230th day after primary covering. 



A chestnut country-bred mare, foaled 6th April, 1859, 14-3J. Sire Bailiff', 



thorough -bred English horse, was cast from the Hapur Remount Depot on the 



21st May 1903, and was received at Muktesar on 26th May, in good health and 



fairly good condition. 



This animal during a period of oestrum was covered by the Arab horse 

 Monarch on the 30th June and 3rd July 1903. At the time of serving the 

 mare on the first occasion, the penis of the stallion was clean and free from* 

 any sores and no symptoms followed the union in the mare ; after the second 

 serving on the 3rd July small ulcers were observed for the first time on the 

 free portion 5 of penis of the horse ; the organ, however, was not noticed to be 

 abnormally enlarged or discoloured. 



4th July. Within a period of 24 hours after the last covering, symptoms 

 of vaginitis had made their appearance. The external surface of the vulva, 

 the inner surface of the labia pudendi and the vaginal mucous-membrane pre- 

 sented vesicles in different stages of development. 



The symptoms of this Vesicular Exanthema affected the external and 

 internal tissues concurrently, but for the sake of clearness the descriptions may 

 be described separately. 



The external manifestations on the vulva were first observed some 18 hours 

 after the last covering, when vesicles were noted to be dotted over the outer 

 surface of the labia pudendi. Twenty-four hours later the eruption of veticles 

 had considerably increased and implicated the surrounding parts in close pro- 

 ximity to those previously affected. 



On the 6th July each individual vesicle appeared upon a raised and 

 swollen base, some more marked than others, the contents of which were then 

 becoming opaque and of a yellowish tinge ; later all formed pustules, which 

 more or less persisted from the 7th to llth inclusive. On the morning (12th) 

 most of the contents of the pustules had become evacuated and open sores or 

 ulcers remained in their place. Twenty-four hours later the process of healing 

 commenced and was maintained under scabs until the morning of the 17th, 

 when some of the latter separated and fell off, leaving patches of leucoderma 

 according to the area of the tissues involved in the inflammatory changes. 

 Between the 18th and 22nd the healing process continued and was completed by 

 the latter date. The primary symptoms of the 4th July affecting the vagina, 

 at before stated, consisted of an eruption of vesicles on a highly inflamed 



