xxxvii 



On the 6th August, the thirty-third day after covering, the first cutaneous 

 plaque was developed on the left side of the abdomen, in the blood of which, 

 on microscopical examination, the trypauosoma was discovered. Between tho 

 above mentioned date and the 20th October, a period of 75 days, a succession 

 of plaques, nineteen in number, made their appearance at intervals, and then 

 ceased ; for, from October 23rd, 1903, to February 29th, 1904, none were 

 observed. 



In fact, with the exception of two slight manifestations of disseminated 

 urticaria, the first implicating the skin of the chest which persisted from the 

 4th to the 6th October, and a second which appeared on the right buttock and 

 remained visible from the 7th to 9th October 1903, no other skin eruptions 

 appeared during the first seven months of the case. 



(Edema of the udder appeared on the 7th October and later it extended 

 forward along the under-surface of the abdomen. In tliis instance, as is so 

 commonly observed in Dourine animals, an alternate increase and diminution in 

 the amount of the swelling and oedema took place, which was gradually ab- 

 sorbed in the former locality, but on the under-surface of the abdomen it per- 

 sisted, and is still present more or less in February. On the 20th September 

 the labia pudendi became slightly patent, arid when at a later date, 2lst October, 

 the vaginal m. m. became much thickened and subsequently oadematous, a 

 small amount of the m. m. protruded from the passage, and from long 

 exposure became dry and discoloured. 



After a period of 8 months liad elapsed, the animal on examination exhibited 

 no signs of weakness in the loins or hind limbs. The external inguinal 

 glands were found to be normal on palpation, the sub-maxillary glands were 

 rather hard and slightly larger than in health, but no nasal symptoms existed. 



On several occasions in January 1904, localized sweating was observed to 

 appear on the neck and shoulders, although at all times absent from other por- 

 tions of the body. 



In addition to the above symptoms, small leucodermic patches existed upon 

 the tissues of the vulva and anus, and the trypanosomata appeared at intervals 

 in the vaginal mucus. 



The temperature of this animal has been recorded twice daily, morning 

 and evening, since the date of its arrival at Muktesar on 31st May 1903, a 

 period of over 8 months. A maximum of 39'2 C. was registered on 1st July, 

 four days previous to the date of covering, and the minimum 37'0 C. on the 

 9th July 1903, four days after being covered by Monarch. Since the 5th 

 July 1903, the evening records varied between 38'4 and 39'1 C, while those 

 of the morning varied between 37'0 and 37'6 C., a difference of only 0'7 and 

 0'6 points respectively. 



