22 



season of the year has a marked effect upon the amount of urine 

 secreted, the tendency being to secrete larger quantities in cold weather 

 than in warm. Combining the data of Series I, III, IV, and V f<j 

 those members completing the series we find that the average daily 

 amount of urine secreted during the fore periods, per individual, is 96J 

 cc, during the preservative periods 960 cc, and during the after period 

 952 cc. These data show 7 almost no effect of the preservatives on th 

 quantity of urine secreted, but there seems to be a slight tendency 

 decrease the amount secreted in the preservative and after periods. 



Albumin. In those few cases w r here there w r as normally a mere trac< 

 of albumin in the urine it is shown by the data that the general tend 

 ency of the preservative used is to increase the trace of albumin in th 

 urine, and this increase is manifested also during the after periods. 



Microscopic bodies. Microscopical examinations of the urine wer 

 made for the following substances : 



Uric acid crystals; Urates ; Oxalate of lime; Phosphates: (a) Crystallin 

 phosphates, (b) Amorphous phosphates; Epithelium cells of all kinds ; Leuccj 

 cytes; Red blood cells; Casts: (a) Hyaline, (b) Finely granular, (c) Coarse! 

 granular, (d) Epithelial, (e) Other forms; Mucous cylindroids ; Mucou 

 strands. 



The microscopic examinations w r ere made at three periods durin 

 each series except in Series I, during which time the microscopic supei 

 vision of the urine had not been instituted. The examinations wer 

 made once during the fore period, once or more during the preservativ 

 period, and once near the close of the after period. 



Reviewing the data as a whole in regard to the appearance of theg 

 microscopical bodies in the urine the facts which appear prominently 

 are the great variations in the number and character of these micrc 

 chemical bodies. They occur constantly in some cases in very muc; 

 greater abundance than in others. There are a few cases, in fact, quit 

 a number, where the relative abundance of these bodies seems to b 

 increased during the administration of the preservative. There is 

 smaller number of cases in which the contrary fact occurs. In th 

 greater number of cases, however, the administration of the preserve 

 tive appears to have had no influence upon the relative abundance o 

 these bodies. The data, therefore, as a whole, can not be regarded ad 

 conclusive respecting the influence of the preservative upon the numbjl 

 or kind of microchemical bodies occurring in the urine. 



THE EFFECT OF THE PRESERVATIVE UPON THE NUMBER OF CORPUSCLES! 

 AND UPON THE HEMOGLOBIN IN THE BLOOD. 



There w r as no regular influence established relating to the effect <x 

 the preservative in increasing or decreasing the number of corpuscle! 

 in the blood. The data in individual cases are often contradictory anc 

 a general summary of them leads to no conclusive result. The final 



