TUMOES. 349 



chest, and en the external genital organs. They are lobulated and contain cells similar 

 to those of the rete Malpighii. Within the cells and crowding the nucleus to one side, 

 or free among the cells, are rounded or ovoid bodies which are believed by many to be 

 protozoan parasites. 



ADAMANTINO.MA (Cystadenoma adamantinum; Epithelioma adamantinum). This 

 group of tumors is of occasional occurrence in the jaws either on the surface beneath 

 the mucous membrane, or in the depth of the bone. They appear to be derived from 

 the enamel organs of developing teeth. They are frequently cystic from the softening 

 and absorption of their tissues and while in general benign may infiltrate the jaw, in- 

 ducing its atrophy. They are most apt to form during the period of the development 

 of the teeth. They consist in general of a fibrillar connective-tissue stroma in Avhich 

 ramify irregular and complex masses of epithelial cells. These epithelial cell masses 

 are made up of rows of cylindrical cells or of superimposed layers of cylindrical, poly- 

 hedral, and flattened cells. Frequently these lamella? of epithelial cells enclose a cen- 

 tral mass of branching cells. The situation of these tumors, their period of formation, 

 and the resemblance of the structure to that in various phases of the evolution of the 

 enamel organ, indicate their origin in some abnormality in the development of the teeth, 

 There is frequently a recurrence after the removal of these tumors and the growth may 

 become sarcomatous. 1 



Bibliography of Tumors. 



The most extensive and important work on tumors, containing a vast store of in- 

 formation, is that of Rudolph Virchow, "Die kraukhaften Geschwiilste." It is not com- 

 pleted and is somewhat old, but is still invaluable as a work of reference. A valuable 

 bibliography and digest of recent observations on tumors will be found in Ziegler's 

 "Lehrbuch der path. Anat.," Bd. i., last edition. An important resume on the malig- 

 nant tumors in childhood, by Stern, may be found in the Deutsche med. Wochenschrift, 

 June 2d, 1892, p. 494. "An Introduction to General Pathology," by Sittton, contains 

 many suggestive facts about tumors drawn from comparative pathology. Current 

 additions to the subject may be found in the files of Lubarsch and Ostertag's "Ergeb- 

 nisse, " see particularly LubarscJi, Jahrg. 1, p. 289, for a comprehensive summary; also 

 for newer bibliography to 1899, Aschoff, Jahrg. 5, for 1898, p. 73. Borst's " Lehre v. d. 

 Geschwiilsten," 1902, is a valuable work with many excellent illustrations; bibl. 



1 See for a resume and bibliography of these tumors, CMbret, Arch, de Med. exp., 

 T. vi , 1894, p. 278; also Borst, Geschwulste, p. 605. 



