THE THYROID AND ADRENALS. 



417 



Pigmentation of the inner cortical zone is frequent iii old persons. 

 Focal necroses may occur in infectious. 



THROMBOSIS AND HAEMORRHAGE. 



Venous and capillary thrombosis may occur. 



In children, soou after birth, it is not very infrequent to find large 



FIG. 217. HEMORRHAGE INTO AND ABOUT THE ADRENAL. (Infant.) 



haemorrhages in one of the adrenals, converting it into a cyst filled with 

 blood (Fig. 217). This lesion has been observed in a few cases in adults. 1 



INFLAMMATION. 



Suppurative inflammation, with the formation of abscesses, has been 

 seen in a few cases. 



The most frequent lesion of the adrenals is tuberculous inflammation. 

 They are usually increased in size ; their surfaces are smooth or nodular. 

 The normal structure of the gland is more or less replaced by tubercle 

 tissue, which usually undergoes cheesy degeneration and may soften. 

 Fibrous tissue may form in considerable amount. (See Addisou's Dis- 

 ease, page 362. )* 



Syphilitic inflammation, with and without the development of gum- 

 mata, is of occasional occurrence. 



1 For bibliography see Arnaitd, Arch. gen. de Med., t. iv., p. 5, 1900. 

 9 For reference to nature of adrenal secretion, etc., see Abel, footnote, page 363. 

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