THE LIVER. 597 



not be visible to the naked eye, or it may appear as grayish, irregu- 

 lar streaks, or bands, or patches, often sharply outlined against the 

 dark-red, or brown, or yellow, or greenish-yellow parenchyma. When, 

 as is often the case, fatty infiltration is associated with atrophic cirrhosis, 

 the liver may not only not be diminished in size but may be larger than 

 normal. 



On microscopical examination the new connective tissue is found in 



FIG. 362. -CHRONIC INTERSTITIAL HEPATITIS CIRRHOSIS. 



On account of the rough surface such livers are sometimes called " hob-nail livers." This cut is a photo* 

 graphic reproduction of a cirrhotic liver of a child. 



some cases loose in texture and containing many variously shaped cells ; 

 or it may be dense and contain comparatively few cells ; it is usually 

 quite vascular. 



The new connective tissue 1 is most abundant between the liver lobules 

 but it may encroach more or less upon their peripheries. Small gall 

 ducts, some of them at least apparently new formed, are usually present 

 in the connective tissue around the islets of parenchyma (Fig. 363). 

 Some of these may usually be found continuous with the old ducts or 

 gall capillaries. Sometimes rows of more or less cuboidal cells in the 



1 For a study of the character of the new connective tissue in cirrhosis see Flexner, 

 University Medical Magazine, vol. xiii., p. 613, 1900. 



