EXPLANATION OF PLATE XIII. 1 



1. NORMAL GANGLION CELL. Large motor cell from anterior horn of human spinal 



cord, showing the nucleus in its normal central position with its nucleolus. In the ( 

 body of the cell are seen the chromophilic bodies of various shapes and sizes. 

 Three main protoplasmic trunks ordendrites pass off from the upper portion of the 

 cell. In these the chromophilic bodies are rod-shaped. The largest process ^ 

 branches at a short distance from the cell. To the left is seen the axone or axis- ' 

 cylinder process free from chromatic substance, as is also that portion of the cell 

 from which it takes origin (axone hill). 



2. GANGLION CELL FROM THE ANTERIOR HORN OF THE HUMAN SPINAL CORD OF A 



CASE OF ALCOHOLIC NEURITIS. Showing eccentricity of the nucleus and a large 

 central area of the cell bod} 7 free from chromatic substance (central chromatolysis), 

 with an arrangement of the remaining chromophilic bodies around the periphery. 

 (The similarity between the appearance of this cell and the one shown in Fig. G 

 should be noted.) 



3. GANGLION CELL FROM THE ANTERIOR HORN OF THE SPINAL CORD OF A RABBIT 



INOCULATED WITH RABIC VIRUS AND KILLED SHORTLY AFTER THE ONSET OF 

 SYMPTOMS. Shows an early stage of chromatolysis ; the chromophilic bodies being 

 pale, ragged, and vacuolated. 



4. GANGLION CELL FROM THE ANTERIOR HORN OF THE SPINAL CORD OF A RABBIT 



WHICH DIED ON THE NINTH DAY AFTER INOCULATION WITH RABIC VIRUS. 

 Shows extreme chromatolysis, only a few fine granules of chromatic substance re- 

 maining at the periphery. The cell is swollen, the nucleus has disappeared, and 

 the cell body and processes are stained more deeply with the erythrosiu than is the 

 case in normal cells. 



5. NORMAL GANGLION CELL FROM A HUMAN SPINAL GANGLION OF THE POSTERIOR 



ROOT. Showing central position of the nucleus and the concentric arrangement of 

 the chromophilic bodies. 



6. GANGLION CELL FROM THE POSTERIOR ROOT GANGLION OF A RABBIT THREE 



WEEKS AFTER SECTION OF THE SCIATIC NERVE. The cell shows extreme eccen 

 tricity of the nucleus with central chromatolysis and a peripheral arrangement of 

 the remaining chromophilic bodies axonal degeneration. (There also remains in 

 the central portion of the cell some chromatic substance in the shape of fine granules 

 forming an irregular reticulum. The similarity between this picture and the one 

 shown in Fig. 2 is apparent.) 



7. PORTION OF A POSTERIOR ROOT GANGLION FROM A CASE OF TABES DORSALIS. 



Showing degeneration in the ganglion cells with increase in the interstitial connec- 

 tive tissue. 



8. Two PYRAMIDAL CELLS FROM THE NORMAL HUMAN CEREBRAL CORTEX. While 



the pyramidal cells in the human cortex vary considerably in the amount of chro- 

 matic substance which thej' contain, these are of an average type. 



9. Two PYRAMIDAL CELLS OF THE HUMAN CEREBRAL CORTEX FROM A CASE OF 



ECLAMPSIA. These cells show marked chromatolysis. 



1 In the staining of the specimens from which these drawings were made. Hold's modification of 

 Nissl's method was used. This consists essentially in a preliminary staining of the sections with a one-per- 

 cent aqueous solution of erytbrosin (see p. 770). 



