AND PERSONALITY 



seen in the adult life of civilized man. It may be regarded 

 as a mutation of the brain and the thyroid gland. Exoph- 

 thalmic goiter involves primarily two organs the large size 

 of which endows civilized man with the distinguishing 

 features of civilization, that is, a high order of intelligence 

 and an equally high order of physical, mental, and emotional 

 activity. 



Exophthalmic goiter could occur in no animal whose 

 brain and whose thyroid gland are so small that the animal 

 could not acquire the civilized state. This is sufficient 

 reason why, in the mortality statistics of Frederik L. Hoff- 

 man, in which are tabulated the causes of death in 1928 of 

 native man throughout the world, in 2,500,000 deaths 

 among a native population aggregating 1,125,000,000 

 people, not a single death from exophthalmic goiter is noted. 

 Nor would there have been a single death from exophthalmic 

 goiter noted among the deaths of billions of horses, cattle, 

 sheep, and swine, or among the deaths of billions of fish, 

 reptiles, birds, and mammals in the wild state. Exophthalmic 

 goiter is found only where there is the highest development 

 of the brain and the thyroid gland, namely, in civilized man, 

 the product of the stimulating climate of the temperate 

 zone. 



In certain adult individuals there occurs, through muta- 

 tion, a state of unbalance resembling exophthalmic goiter. 

 In these individuals the heart palpitates without obvious 

 cause from the environment, the victims vacillating be- 

 tween intense mental and emotional excitability, exhaus- 

 tion, and complete breakdown. This condition is known as 

 neurocirculatory asthenia, or " soldier's heart." In this 

 group are to be found some of the brilliant and interesting 

 invalids of history. During the First World War many such 

 cases were seen. The army mule could not acquire neuro- 

 circulatory asthenia. Neurocirculatory asthenia is a muta- 

 tion of the brain-adrenal-sympathetic system. Victims of 

 neurocirculatory asthenia exhibit all the symptoms of 



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