dominance of the exophthalmic goiter victim and the 

 dominance of the celiac ganglia, plexuses, and heart of 

 the victim of essential hypertension and coronary disease. 



In this fourth group we see an example of a competent 

 thinking brain, driven to a high level of activity by a well- 

 balanced thyroid gland and adrenal-sympathetic system. 

 The individuals of this group are more prone to ambition 

 and worry than is the more stable candidate for essential 

 hypertension and coronary disease. 



Peptic ulcer occurs more commonly in men, particularly 

 in those who are under stress because of their occupations 

 or in individuals who, struggling under conditions of 

 conflict, discouragement, or maladjustment, are especially 

 subject to worry, anxiety, and fatigue. Exophthalmic 

 goiter occurs more commonly in women. Peptic ulcer 

 appears in the midst of the active careers of ambitious 

 men. Exophthalmic goiter appears in the midst of the 

 domestic worry and the social drive of women. 



The fifth mutation, diabetes, is a synthesis of an active 

 brain and a high normal thyroid-adrenal-sympathetic sys- 

 tem. It is most commonly found among active and success- 

 ful individuals. The childhood of a diabetic is characterized 

 by a brilliant scholastic career and, on an average, a 

 diabetic child is two years ahead of his grade. Diabetes 

 does not produce brilliant minds, but brilliant people may 

 tend to acquire diabetes. Many of the outstanding per- 

 sonalities in history have been diabetics. 



In this connection it is interesting to note that in exoph- 

 thalmic goiter the incidence of diabetes and disturbed car- 

 bohydrate metabolism is far higher than in the population. 



The victims of these five mutations are characterized by 

 the highest qualifications seen in civilized man. These 

 mutants represent the most progressive, the most inventive, 

 the most valorous fraction of civilized man. They are con- 

 spicuous in the professions, in government, in business, 



264 



