APOCYNUM 17 



Bridge of London. Anise is mentioned in the expenses 

 of King John of France, 1319-1364, during his abode 

 in England. The Grocers' Company of London had 

 its oversight, 1453. The Royal Wardrobe of Edward 

 IV, 1480, was perfumed thereby. It was used in Eng- 

 land as a pot herb prior to 1542, and during the reign 

 of Charlemagne it was enormously taxed. Through- 

 out all this period anise was employed both as a spice 

 and as a domestic medicine. 



ANTHEMIS (Anthemis, Chamomile) 

 Official from 1820 to 1900. Dropped from Pharmacopeia of 

 1910. 



Anthemis nobilis has been cultivated for centuries in 

 English gardens, and from the beginning of the records 

 it has been used in domestic medicine. It was intro- 

 duced into Germany from Spain about the close of the 

 Middle Ages. It is now grown in favorable localities 

 throughout every section of Europe, and especially in 

 Saxony, as well as in Belgium and France. The name 

 Roman Chamomile was given the drug growing near 

 Rome, by Joachim Camerarius (120), 1598. 



APOCYNUM ("Indian Hemp," "Canadian Hemp") 



All editions of the U. S. P. excepting that of 1910 recognize 

 Apocynum, but until 1880 it appears only in the Secondary List. 

 The early editions, 1820, 1828 and 1830 (New York), give place 

 only to Apocynum androscemifolium, "Dogsbane," a variety now 

 so rare that it can scarcely be obtained, even as a museum speci- 

 men. The variety Apocynum cannabinum, "Indian Hemp" is 

 mentioned first in the Philadelphia edition of 1830. This, like all 

 editions following, until 1870, carries both varieties. The 1880 

 edition limits Apocynum to the variety cannabinum, which it 

 designates as "Canadian Hemp." This limitation is followed in 

 1890, while the edition of 1900 admits "Apocynum cannabinum 

 and closely related species of Apocynum." 



"American Indian Hemp" is the name given to pos- 

 sibly a score of closely related plants, all known as 



