136 PHARMACOPEIAL DRUGS 



century after the resinoids of America received their 

 deathblow at the hands of the Eclectics, a peculiar 

 craze for Euonymin struck England. The American 

 manufacturers' lists quote two colors of the drug, one 

 green and the other brown. These two forms came into 

 English demand, and owing largely to their exploitation 

 by the celebrated Dr. Richardson, of London, so great 

 was the 'Euonymin' craze in that country, that within 

 a brief period American resinoid makers were over- 

 whelmed with orders for the drug. The root, root-bark, 

 shrub, and the shrub-bark supplies of the crude drug 

 employed for their manipulation became exhausted, 

 whilst the price of all forms of the crude drug doubled 

 and trebled. We know of single orders from London 

 for one thousand pounds, each color of Euonymin, 

 quick delivery. From 1885 to 1890 the English Euony- 

 min craze was at its height, and during those years the 

 English pharmaceutical and medical press teemed with 

 articles concerning the wonderful remedy! The various 

 Euonymins were examined for ash, and the old question 

 of inorganic admixture was naturally revived, especially 

 with the green-colored drug, where aluminum hydroxide 

 is likely to be employed to precipitate the chlorophyl- 

 bearing structures and associated materials from the 

 evaporated alcohol extract, said hydroxide contaminat- 

 ing the product. It was even reported that one lot of 

 Euonymin contained much barium carbonate, a state- 

 ment difficult to accept!" 



As abruptly as it began did the English concentration 

 fad terminate, leaving but a few energetic resinoids, 

 such as King's Resin of Podophyllum (representative 

 of the class), still used in England, as it is both used as 

 well as abused today in all parts of the civilized world, 



